one2wonder, Let me preface this by saying I would *never* condone anyone willy nilly trying
different doses on their meds themselves w/o med supervision. However, since the holistic doc was initially going to put me on 100 syn and 5 cyto, which would be the equivalent to 120 of straight Synthroid, and I had already been on 88syn/10cyto (equiv to roughly 128 Synthroid).
This seems like a logical plan given your TSH response and Fts being in normal range. I am debating on whether to try this for a few days before I go to endo on Tues to see if this is the answer. If it would work, then I could fess up and tell him what I did and see what he says.
I wouldn't add the cytomel back in until after your latest round of testing. 1. How long does Cytomel stay in the blood stream? Maker site says biological half life is 2.5 days. Does that mean 2.5 days it stays in blood stream?
depending on your thyroid state (hypo/normal/hyper) you can have a half-life of >2/2/<2 days. This means that you should at least give your body a week or two to purge the cytomel. After 2 days you will be at 50 concentration, 4 days 25%, 6 days 12.5%, 8 days 6.25%, 10 days 3.125%.. you get the picture. After 9 days you are with in the error limit of the tests and thus can safely assume that the cytomel remaining is negligible to the accuracy of the tests. If a Total T3 testing regime is used.. 5 days is sufficient. 2. If I were to do this, how long do you think before I would feel any different. The Cytomel info on the maker's website says max pharmacologic response is 2-3 days. Does that mean 2-3 days before I may feel different?
Okay it takes your body 7-10 days to hit equilibrium on a T3 supplement if you are HYPO.. if you are not the adjustment is quicker 5-7 days. You should notice a difference with the T3 with in a matter of days. It just takes your body longer to determine if the difference will be enough. 3. It is the chicken or the egg thing too...Did they hypo mess up the adrenals or did I have the adrenal thing previously...
Unknown and not enough information to determine this. you need cortisol and ACTH and other hormonal studies regularly to determine the health/reactivity of you adrenals.
September (while on 100 Synthroid only)
Free T4 1.7 (.8-1.8)
Free T3 307 (230-420)
TSH .76 (.4-4.50)
TPO AB 463
November (while on .88mcg Synthroid, 10mcg Cytomel, 200mg Progesterone 18days/mo)
Free T4 1.2 (.8-1.8)
Free T3 325 (230-420)
TSH .22 (.4-4.50)
TPO AB 411[/QUOTE]
Your antibody levels are consistent no matter the dosage. The FT4 level drop may be due to excess estrogen binding up T4 given the progesterone. your T3 levels are better on the 10 mcg of cytomel. Would it be possible to try a median T4 dose of 94mcgs? You can take half a 100 and half an 88 to get this amount. I might see about trying a 94 mcg and 10 mcg combination. Especially if you test your estrogen levels and they are high. You should also have them look into your thyroid binding hormone potential.. now the MD may balk.. you have to persuade them to work with you.