Hi, first post here. This looks like a board with helpful and knowledgeable people, please help me with comments or suggestions.
50+ yo female
multinodular goiter with one prominent nodule
two FNAs, both non-diagnostic
symptoms of hypothyroid
recently started on unithroid 0.10
type 2 diabetes
25 year history of hypertension
Hi, Missy! Welcome aboard. I would love to interpret your results, but there is a bit of vital information missing. The lab ranges that are on the lab sheet with the results give us a clue whether your results are high, low, right in the middle, etc. Since these ranges vary from lab to lab and even by region if you are using the same lab, the results are open to interpretation based on the ranges.
The one thing that I will comment on is that you TSH, while not terribly high is higher than what most health adults would have. TSH doesn't directly correlate with symptoms, but usually, someone with on eas high as yours will have some symptoms. According to a recent study, the average normal healthy adult with no thyroid problems has a TSH near 1.5, though this can fluctuate throughout the day.
TSH is your body signaling the thyroid glad that you need more thyroid hormones, and this is how it is significant. This means that your body is asking the thyroid gland to work harder than the average person, and this can cause some swelling and can cause nodules to grow in some cases. The idea behind treating you at this point is to let your thyroid rest and then, in most cases, the nodules will shrink.
If you can provide the lab ranges, we can dig a little deeper.
Meep, thank you for your response, this is what I think you wanted.
TSH 4.64 (0.32-5.0 uIU/ml)
FTI 7.4 (5.4-9.7 ug/dL)
T4 total 7.8 (5.6-13.7 ug/dL)
T3 uptake 0.95 (0.79-1.16 % uptake)
The multinodular goiter was diagnosed about 5 years ago. I was on suppression therapy for over a year, the thyroid and nodule size did not change. (I don't remember lab values from that time.) I went for a long time with no health insurance, now I am insured again and am being evaluated by another doctor.
The nodule has increased in size, the thyroid has also changed in size since the ultrasound I had several years ago. One lobe is larger, the other is smaller. Yikes!
The endo doctor felt I had hypo symptoms, and after discussion, I agreed to suppression therapy again. I will be evaluated in six weeks with another US. I am not especially concerned about the nodule in spite of my sister having papillary thyroid cancer 10 years ago. She was young and had a solitary nodule, not like me. <IMG SRC="http://www.healthboards.com/ubb/smile.gif">
Welcome, Missy. It's best for Meep to follow-up on these blood tests, but I wanted to ask if you have ever been evaluated for thyroid antibodies? It's yet another blood test, but it could be helpful in determining why you've developed this goiter (as well as explaining why you're symptomatic even with blood levels within the lab's "normal" ranges). Antibodies and thyroid disease are hereditary, which may explain your sister's disease as well.
If you've not yet had a chance, browse through our Information Archive thread. On Page 2 there are some links about Selenium and Maca, two options that are helpful in fighting thyroid antibodies (and support the immune system even in the absence of antibodies). There are also symptoms lists that may sound familiar to you.
<A HREF="http://www.healthboards.com/ubb/Forum118/HTML/000005.html" TARGET=_blank>http://www.healthboards.com/ubb/Forum118/HTML/000005.html</A>
Also, since your dominant nodule has grown and the FNAs have been inconclusive, it may be time for additional study such as an ultrasound and/or Iodine Uptake Scan. An uptake scan in particular may be helpful in determining if the nodule consists of hormone-producing thyroid tissue ("hot" or "warm" nodule) or if it is something else. You may already be familiar with the process because of your sister's experience, but EndocrineWeb explains it quite well:
<A HREF="http://www.endocrineweb.com/" TARGET=_blank>http://www.endocrineweb.com/</A>
[Click on the "Your Thyroid" link to start.]
You can do searches for some of their more hidden webpages, such as "tests," but it's a rather comprehensive site.