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Old 02-20-2012, 09:47 AM   #1
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Elevated Thyroglobulin level after thyroidectomy

I was diagnosed with thyroid cancer and had a complete thyroidectomy in September of 2011. Following the surgery I had treatment with radioactive iodine and a scan done in November 2011 showed I was cancer free.

I was told today that a check of my antibodies shows elevated thyroglobulin levels. Does that mean the cancer is back? I hate to jump to conclusions, but I'm scared.

 
Old 02-20-2012, 11:39 AM   #2
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Re: Elevated Thyroglobulin level after thyroidectomy

There are two different tests---thyroglobulin, and then thyroglobulin antibodies---were your antibodies elevated, or the tg levels themselves? What were your baseline results prior to surgery in the antibodies?

Has your tsh been suppressed since the RAI? (below .05) Was the tg tested with thyrogen/high tsh, or your suppressed one?

Normally, tg levels that are detectable, indicate active thyroid tissue, so if it was all destroyed in RAI, there should be none. However, you need to discuss the antibodies in more detail with your doctor, because the antibodies call the tg use as a "tumor marker" into question---it makes it less accurate.

You need to discuss this further with the doctor, and perhaps get a second opinion before you do anything further (cancer center, MD anderson, Sloan etc)---if the doctor is thinking the thyroid tissue is RAI resistant, which was why the RAI scan was clear, but the blood levels detectable, then they may want to confirm with a PET scan.

I doubt you have a "recurrence" at this stage---, I think you need to research further with experts in thyroid cancer---you can find many educated ones at the thyroid cancer organization.

 
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