Please Help! Cannot tolerate T3 medication and when taking T4 there is weight gain?
What does it mean when a person cannot tolerate T3 medication and when they take T4, they get fatter?
I had a subacute thyroiditis a couple years ago. I don't feel like I am 100 percent recovered. When I take anything with T3, even a small amount, I get major anxiety, mood swings, and become very emotional. When I take T4-only (Synthroid 50 mcg), I gained 25 lbs in two months and increased my RT3 level.
I don't know what to do. I feel like gaining 25 lbs in two months on Synthroid that maybe my body does not want the thryoid drugs? I never tested positive for ANY antibodies, tpo or ag. I never had any family history either.
Can anyone help me and provide some explanation behind their reasoning? I don't want to spend the rest of my life on the couch.
Here are my labs when I am on and off thyroid hormone:
02/06/12 Lab Tests
TSH 2.79 (Range: 0.40 - 4.50 mIU/L)
Free T4 1.0 (Range: 0.8 - 1.8 ng/dL) (20 percent of range)
Free T3 2.8 (Range: 2.3 - 4.2 pg/mL) (26.3 percent of range)
Reverse T3 20 (11-32 ng/dL)
Thyroid Antibodies (ATA, TPO) NONE
RT3 ratio: 14
02/15/12 *****PUT ON 50 MCG of SYNTHROID*****
03/27/12 Lab Tests
TSH 2.77 (Range: 0.40 - 4.50)
Free T4 1.2 (Range: 0.8 - 1.8) (40 percent of range)
Free T3 3.5 (Range: 2.3 - 4.2) (63.2 percent of range)
Reverse T3 27 (11-32)
RT3 ratio: 13
Oh, and I had my sister who is similar in age, never had children, runs everyday, and weighs about 115 lbs -- in other words, very healthy -- get her labs done and here is what they were:
TSH 3.12 (Range: 0.45 - 4.5)
Free T4 1.06 (Range: 0.82 - 1.77) (25.2 percent of range)
Free T3 2.5 (2.0 - 4.4) (20.83 percent of range)
I feel like my labs are BETTER than hers, which blows my mind. Then, I think well maybe I have a different kind of problem if her labs are worse than mine and she is perfectly fine.