Anyone with any experience with xenadrine EFX? I would love any info. In the past I have taken products that had ephedrine in them and they definitely helped me lose weight,however, I started having problems with anxiety and had to quite taking the ephedrine. I think that it might have been the cause for the anxiety but am not positive. Anyway, I did find out that the EFX substitutes the ephedrine with synephrine and like anything else every piece of info I have seen has a different opinion. If anyone out there is taking this product and an anti-depressant such as zoloft I would like to hear from you especially. There is not much sense in asking my doctor since I have never meet a doctor that was an advocate of any of the over the counter diet pills that are out there.