oh yeah. I am on depo and every now and then my blow up like big balloons and oh wow do they hurt! Especially when I take my underwire bra off or when I get up in the morning. I had one run with it where they were like that for a month! I went up a whole cup size (course my hubby loved that
) Whenever I complain about my boobs hurting mom, or hubby will ask if I could be pregnant. Well, if I get a scare like that (I don't get my period with depo) I run out and get a test.
Luckily, mine are back to normal, hubby misses the size, but I don't miss the pain!