I has 2 injections (3 months each) of Lupron. I was on it not for Endo but because I was anemic from bleeding from a fibroid and my ob/gyn wanted to stop the bleeding after he removed the fibroid so my body could recover and my blood count could be restored.
Overall, I liked being on it. I didn't have too many side effects like I have heard other people have. Guess it depends on each individual person. I had hot flashes and some weight gain but that's it. No headaches or moodiness.