My name is A.Moradi and I am an Iranian citizen. I have been suffering from an unknown disease. About 20 months ago suddenly I felt tinnitus and hearing loss in my right ear and 4 months later my left ear was involved too. Meanwhile the field of my vision in my left eye was decreased. In enclosure you will find a summary of my medical records and documents prepared by one of my physicians .
Furthermore up to now various treatments have not changed the above symptoms.
Your kindly and prompt guidance would be highly appreciated.
Yours truly
Abbasali Moradi
Abasmoradi@yahoo.com
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Mr.Abbasali Moradi,34 years old,with painless aphthous lesions of mouth and paresthesia of hands more on the left side, and also around mouth underwent CT of brain which was reported normal(3.11.75=22.1.1997).
Then he suffered headache and nausea relieved by vomiting, received propranolol, amitriptyline, flouxetine for migrain.
He also suffered tinnitus and decreased hearing on right side,also showed on audiometry (13.11.77 = 1.2.1999) ABR showed right cochlear lesion. (18.11.77 = 6.2.1999) .He received prednisolon, Betahistine chlordiazpoxide, Nicotinic acid. Tinnitus decreased no change for hearing that also effected his left ear too (29.3.78 = 18.4.1999) He also suffered from eye that was due to ischemic optic atrophy on left side (1.4.78 = 21.6.1999) M.R.I (5.4.78 = 25.6.1999) showed few UBO, pluses of methylprednisolon started for multiple sclerosis. ETF(7.5.78 = 28.7.1999),VEP,SEV,AEP were all within normal limits.(7.9.78 = 27.11.1999) .
MRI with gadolinium (28.9.78 = 18.12.1999) was normal . He was put on MTX, folicacid , prednisolon for autoimmune inner ear disease. Spiral CT (5.11.78 = 24.1.2000) showed left vertebrel occlusion , trental was started.
DR.H.Elyassi
MD internist
Different tests made are as follows:
24/5/1999
Hematology
Test Result Units Normal Range Differential
W.B.C 9,300 /cumm Neutrophils 70 %
Hemoglobing 15.4 g/dl Lymphocytes 27 %
Hematocrit 46 Ratio Eosinophil 2 %
Monocyte 1 %
Total 100
ESR 1st hr 5 mm
R . B. C. Morphlogy . Normal
Platelets Adequate
Biochemistry
Test Result Units Normal Range
Fasting Blood sugar 88 mg/d1 70-110
Urea........................ 22 mg/d1 15-45
Creatinin................. 0.75 mg/d1 0.5-1.5
Uric acid................. 4.2 mg/d1 M 4 - 8
F 3 - 7
Cholestrol............... 200 mg/d1 150-270
Triglycerides.......... 169 mg/d1 60-170
L .D .L cholestrol... 104 mgs/d1 Desirable level 160
H .D .L cholestrol... 62 mg/d1 M 30 - 60
F 40 - 70
LDL/HDL............... 1.6 Ratio Less than 3
Cholestrol / H .D .L 3.2 Ratio Low risk 3 . 3 - 4 .4
Avrege risk 4 .4 -7 .11
Moderate risk 7.1 -11
High risk > 11
Urinalysis
Macroscopic Microscopic
Color Yellow W. B . C . 0-1
Appearance Clear R . B . C . 0
Specific gravity 1015 Epithelial cells 0-1
PH 5 Bacteria Neg .
Proteins Neg . Mucus Neg .
Glucose Neg . Casts Neg .
Ketones Neg .
Blood . Neg .
Bilirubin Neg .
Urobilinogen Neg .
Nitrite Neg .
7/8/1999
Immunology
Test Result Units Normal Range
C3......................................... 97 mg/d1 50 - 120
C4......................................... 21 mg/d1 20 - 50
CH50.................................... 52 %pool 70 - 130
Anti Nuclear Ab ( IF ) ...... Negative Negative
Hematology
Test Result Units Normal Range Differential
WBC 7200 /cu mm 4000-10500 Seg 54 %
RBC 4.87 Mil/cumm 3.5 - 6.0 Lymphocytes 40 %
Hb 13.4 g/dl 11.5-14.4 Monocytes 5 %
HCT 42.0 % 35-51 Eosinophils 1%
MCV 86.2 76-96 Total 100
MCH 27.5 27-32
MCHC 31.9 32-36
Platelete count 276000 /cu mm 150000-450000
ESR 1 St hr . 12 m . m Males : 0 - 13 mm in 1 hour
Female : 0 - 20 mm in 1 hour
LE.Cell Negative
Scrology
Test Result Units Normal Range
Wright agglutination test 1/20
VDRL ........................... Negative
Immunology
Test Result Units Normal Range
Anti HIV ( 1&2 )........... Negative
Immunology
Test Result Units Normal Range
HLA B5 ,B27,B8................
B5 ..................................... Positive
B27 ................................... Negative
B8 ..................................... Negative
15/12/1999
Serum Serology
Test Result Units Significant Ranges
ANTI NUCLEARANTIBODY IF.................. Negative 1:10-1:40=1+,upto1:160:2+,upto ; 1:320:3+ ,>1:320:4
ANTI NEUTROPHIL CYTOPLASMIC Ab... Negative
Syphilis Screenig test ( Elisa )........................ None Reactive
Serum Immuno & Chem . 2
Test Result Units Normal Range
CH50 94 % 90-100
22/1/2000
Immunology
Test Result Units Normal Range
C3......................................... 119 mg/d1 50 - 120
C4......................................... 25.5 mg/d1 20 - 50
Cryoglobulin........................ Negative Negative
Coagulation
Test Result Units Normal Range Differential
Protein C Activity 126 % 70-130
Protein S Activity 152 % 65-140
Antithrombin III Activity 119 % 80-120
13/2/2000
Urinalysis
Macroscopic Microscopic
Color Yellow R . B . C 0-1
Appearance Clear W. B . C . 0-1
Specific gravity 1026 Epithelial cells 0-1
PH 6 Bacteria Few .
Proteins Neg . Carystals Neg .
Glucose Neg . Casts Neg .
Ketones Neg . Mucus Little
Blood . Neg .
Bilirubin Neg .
Urobilinogen Neg .
Nitrite Neg .
Immunology
Test Result Units Normal Range
Anti Nuclear Ab ( IF ) ...... Negative Negative
Serology
Test Result Units Normal Range
C- Reactive Protein....... Negative
R . A Factor , RF latex . Negative
Hematology
Test Result Units Normal Range Differential
WBC 11300 /cu mm 4400-11000 Seg 64 %
RBC 5.52 Mil/cumm male: 4.5-5.9 Lymphocytes 27 %
Female : 4.5-5.1 Monocytes 7 %
Hb 14.8 g/dl male: 14-17.5 Eosinophils 2 %
Female : 12.3-15.3 Total 100
HCT 47.1 % male: 41.5-50.4
Female : 35.9-44.6
MCV 85.3 80-96
MCH 26.8 27.5-33.2
MCHC 31.4 33.4-35.5
Platelete 233000 /cu mm 150000-450000
ESR 1 St hr . 6 m . m Males : 0 -15 mm in 1 hour
Biochemistry
Test Result Units Normal Range
Blood Urea Nitrogen......... 14 mg/d1 8-23
Creatinin............................ 0.8 mg/d1 0.7-1.4
Uric Acid........................... 4.7 mg/d1 Male : 4.3-8
Female : 2.3-6
Cholestrol.......................... *263 mg/d1 Less than 200
Triglycerides................. 207 mg/d1 40-150
S . G . O .T ( AST ) ...... *19 IU/L 5-40
S . G . P .T ( ALT ) ...... *44 IU/L 5-40
Alkaline phosphatase 115 IU/L Adult : 70-306
Child Up to 15 years 180-1200
Comment : *Rechecked
15/3/2000
Hematology
Test Result Units Normal Range Differential
WBC 11300 /cu mm 4400-11000 Seg 68 %
RBC 5.42 Mil/cumm male: 4.5-5.9 Band Cells 1 %
Female : 4.5-5.1 Lymphocytes 29 %
Hb 15.0 g/dl male: 14-17.5 Monocytes 2 %
Female : 12.3-15.3 Total 100
HCT 46.9 % male: 41.5-50.4
Female : 35.9-44.6
MCV 86.5 80-96
MCH 27.7 27.5-33.2
MCHC 32.0 33.4-35.5
Platelete Count 246000 /cu mm 150000-450000
PT . patient 12.3 Sec 11-14
PT . Normal 13 Sec 11-14
PT . activity 100 %
INR 1 1-1.3
Biochemistry
Test Result Units Normal Range
Blood Urea Nitrogen......... 10 mg/d1 8-23
Creatinin............................ 1 mg/d1 0.7-1.4
S . G . O .T ( AST ) ...... 20 IU/L 5-40
S . G . P .T ( ALT ) ...... 30 IU/L 5-40
Alkaline phosphatase 123 IU/L Adult : 70-306
12/4/2000
Hematology
Test Result Units Normal
Bleeding Time ................................ 2. 30 Minutes
Clotting Time.................................. 7. 00 Minutes
Patient ‘s Prothrombin Time ........... 12 . 0 Sec
Control ............................................. 12 . 0 Sec
Percent PT......................................... 100 %
INR.................................................... 1 . 0
A . P . T . T........................................ 38 Sec 30-40
3/5/2000
Hematology ( CBC )
Test Result Normal WBC DIFFERENTIAL RBC MORPHOLOGY
WBC 9 4.0-10.0 x1000 Neutrophil : 87 Anisochromia : Slight
RBC 4.88 M 4.5-6.3 F 4.2-5.4X100000 Lymphocyte : 11
Monocyte : 2
HGB 14. 6 M 14-18 F 12-16 g/dl
--------------------------------------------------------------------------------
HCT 44. 6 M 39-52 F 36-46 %
MCV 91. 4 83 - 97 micr3
MCH 29. 9 26 - 32 pg SedRate 1 Hr : 4 mm/ Hour
MCHC 32. 7 32 - 36 %
PLT 185 140 - 400 x1000
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Hematology
Test Result Units Normal Range Differential
PTT- Patient 31” Sec 30-45
Prothrombin Time 12”Activity 100%
P.T control 12”Activity 100%
Serology
Test Result Units Normal Range
Anti Phospholipid - Ab ( lgG ). 12 GPL Unit 10 - 20 - 80 : Medium Positive
> 80 : High Positive
ANCA.................................. Negative
Immunology
Test Result Units Normal Range
Chlamydia....................... 0.76 Index 1.1 : Positive
Test Result Units Normal Range
Lupus anticoagulant Negative
Skin Tests
Test Result Units Normal Range
Anti Cardiolipin ( lgG ) 3 30 : Positive
Anti Cardiolipin ( lgM ) 16 30 : Positive
Immunology
Test Result Units Normal Range
--------------------------------------------------------------------------------
CH50.................................... 18 %pool 70 - 130
--------------------------------------------------------------------------------
ANCA ( IF ) ........................ Negative Negative
20/5/2000
Hematology ( CBC )
Test Result Normal WBC DIFFERENTIAL RBC MORPHOLOGY
WBC 5. 9 4.0-10.0 x1000 Neutrophi : 60
RBC 4.78 M 4.5-6.3 F 4.2-5.4X100000 Lymphocyte : 36
Monocyte : 4 Unremarkable morphology of RBC
HGB 14. 5 M 14-18 F 12-16 g/dl
--------------------------------------------------------------------------------
HCT 44. 3 M 39-52 F 36-46 %
MCV 92. 7 83 - 97 micr3
MCH 30. 3 26 - 32 pg SedRate 1 Hr : 5 mm/ Hour
MCHC 32. 7 32 - 36 %
PLT 207 140 - 400 x1000
--------------------------------------------------------------------------------
20/5/2000
Biochemistry
Test Result Units Normal Range
Fasting Blood sugar ( FBS ).................... 102 mg/d1 70-110
BLOOD UREA NITROGEN ( BUN )... 10 mg/d1 Adult : 8-20 , Children : 5 - 25
CREATINIE .......................................... 1.1 mg/d1 0.4 - 1.3
SGOT ( AST ) ....................................... 23 IU/L Up to 42
SGPT ( ALT ) ....................................... 24 IU/L Up to 38
ALKALINE PHOSPHATASE.............. 88 IU/L Adults : 45 - 150 : Up to 17 : 45 -450
Urineanalysis
Macroscopic Microscopic
Color Yellow W. B . C ./HPF 0-1
Appearance Clear R . B . C ./HPF 0-1
Reaction ( PH ) Alk EP . Cells 1-2
Specific Gravity 1.028 Mucus ----
Albumin Negative Cast ----
Sugar Negative Bacteria ----
Crystals ----
Other ----
10/7/2000
Biochemistry
Test Result Units Normal Range
FASTING BLOOD SUGAR ( FBS )...... 98 mg/d1 70-110
BLOOD UREA NITROGEN ( BUN )... 10 mg/d1 Adult : 8-20 , Children : 5 - 25
CREATINIE .......................................... 1.0 mg/d1 0.4 - 1.3
SGOT ( AST ) ....................................... 28 IU/L Up to 42
SGPT ( ALT ) ....................................... 22 IU/L Up to 38
ALKALINE PHOSPHATASE.............. 78 IU/L Adults : 45 - 150 : Up to 17 : 45 -450
Hematology ( CBC )
Test Result Normal WBC DIFFERENTIAL RBC MORPHOLOGY
WBC 5. 2 4.0-10.0 x1000 Neutrophi : 59
RBC 4. 55 M 4.5-6.3 F 4.2-5.4X100000 Lymphocyte : 39
Monocyte : 2 Unremarkable morphology of RBC
HGB 13. 9 M 14-18 F 12-16 g/dl
--------------------------------------------------------------------------------
HCT 41. 5 M 39-52 F 36-46 %
MCV 91. 2 83 - 97 micr3
MCH 30. 5 26 - 32 pg SedRate 1 Hr : 10 mm/ Hour
MCHC 33 . 5 32 - 36 %
PLT 216 140 - 400 x1000
--------------------------------------------------------------------------------
Hematology Coagulation
Test Result Units Normal Range
Patient ‘s Prothrombin Time ........... 12 . 0 Sec
Control ............................................. 12 . 0 Sec
Percent PT......................................... 100 %
INR.................................................... 1 . 0
A . P . T . T........................................ 38 Sec 30-40
10/7/2000
Urine Analysis
Macroscopic Microscopic
Color Yellow W. B . C ./HPF 0-1
Appearance Clear R . B . C ./HPF 0-1
Reaction ( PH ) Alk EP . Cells 1-2
Specific Gravity 1.028 Mucus ----
Albumin Negative Cast ----
Sugar Negative Bacteria ----
Crystals ----
Serology
Test Result Units Signigicant Ranges
C- REACTIVE PROTEIN ( CRP ).................. Negative
28/9/2000
Serology
Test Result Units Signigicant Ranges
H . B . S Ag ( ELISA ) ............................ Negative
HBS Ab ( ELISA ) ................................... 16 MIU/ml Negative 10