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Posted by artemis on August 09, 2000 at 18:36:19:

In Reply to: question for artemis posted by diana on August 09, 2000 at 13:17:22:

Diana,
This response I am giving you is "after the fact" as there was no time to think about this at the time my husband received whole brain radiation. With brain mets present at the start, the fear of other cells apparently was too great. However, I have read much since athen so that is what I am relaying - it is also based on others w/sclc that have had brain mets after their initial diagnosis. Today, I would look into gamma knife surgery and/or sterotactic radiation. The stereotactic radiation is applied directly to the mets, as opposed to the whole brain. The consequence of whole brain radiation for my husband has been short-term memory loss, so if it can be avoided, I would. As far as chemo's - there is one called Temodar - in pill form - that the neurologist mentioned. It's fairly new and was not developed specifically for lung cancer brain mets, but apparently is showing promise. Also, there is something called "intrathecal" chemo. It uses a drug called Methotrexate, injected either in the spinal fluid or in a reservoir in the brain. Again, this option avoids the consequences of whole brain radiation. These would be my suggestions. Feel free to write me directly at artemis@online-pro.com if I can be of further help. My best to you.


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