Posted by
LpLittleA on November 04, 2000 at 00:12:18:
American Journal of Cardiology
High carbohydrate diets, triglyceride-rich lipoproteins, and coronary heart disease risk
Effects of variations in dietary fat and carbohydrate content on fasting lipid and lipoprotein concentrations were compared in 8 healthy volunteers. As a percent of total calories the diets contained either 60% carbohydrates, 25% fat, and 15% protein, or 40% carbohydates, 45% fat, and 15% protein. Diets were consumed in random order for 2 weeks separated by a 2-week washout period.
Results:
The 60% carbohydrate diet resulted in significantly higher levels of fasting plasma triglyceride, remnant lipoprotein cholesterol, remnant lipoprotein triglyceride, and lower HDL-C, with no change in LDL-C.
The changes in plasma triglyceride, remnant lipoprotein cholesterol, and remnant lipoprotein triglyceride persisted throughout the day in response to breakfast and lunch.
Conclusion: Substituting carbohydrate for saturated fat results in higher plasma triglyceride and lower HDL-C associated with day-long increases in circulating triglyceride and remnant lipoprotein concentrations. These changes are potentially atherogenic.
( American Journal of Cardiology 2000; 85(1); 45-48)
