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Posted by Ken
on September 05, 2000 at 20:30:22:
In Reply to: Protienurea posted by K.Colleen on July 04, 2000 at 17:54:31:
: What is protienurea? I have been told that the protien levels in my urine are high. What does that mean? My doctor suggested that I just have it monitered every six months. Is this something I should be concerned about?
Hi. Proteinuria means protein exceeds a threshold level in your urine and it means your kidney is not filtering correctly. Proteinuria starts as microalbuminuria and progresses to proteinuria. Proteinuria can lead to kidney failure and you need to be aggressive in halting the proteinuria. You should be concerned. It means there is too high a pressure in you kidneys from conditions such as hypertension. If your problem is rooted in hypertension you need to take an ARB or ACE inhibitor immediately to reduce your renal vascular resistance and reduce filtration fraction, thus reducing protein. Drugs such as ARBs have no side effects so I would suggest them first line. Atacand an ARB is the most potent of the ARBs and has showed reductions of urinary albumin excretion of 57% only after 12 weeks of therapy.
Proteinuria can lead to fibrosis and sclerosis of your existing glomeruli (bundles of vasculature that enable filtration of urine.) Once a glomerulus is sclerosed, it no longer functions. So I suggest that you see a nephrologist (kidney specialist) and ask for an ARB if you have hypertension.
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