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Re: western blot and elisa

Re: western blot and elisa

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Posted by M.A. on October 02, 1999 at 14:38:48:

In Reply to: western blot and elisa posted by Nancy on October 01, 1999 at 00:06:43:

According to the book "Everything You Need to Know About Lyme Disease," to qualify for a recent infection, a patient needs 2 of the 3 following IgM bands: 23/25kD, 39kD, 41kD. To qualify for longer standing infection, needs 5 of the 10 following Bb IgG bands: 18kD, 21kD, 28kD, 30kD, 39kD, 41kD, 45kD, 58kD,66kD, 93kD. All of these are based on strains B31, 297, 2591. Other strains may make other bands. A positive ELISA is usually confirmed with a western blot, but I think many people who have Lyme have had any combination of positives and/or negative results.

I highly recommend this book for a good overview of Lyme Disease. The auther is Karen Vanderhoof-Forschner who also founded the Lyme Disease Foundation.


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