Re: Dr. Whitworth, Oxycontin Titration question

In Reply to: Dr. Whitworth, Oxycontin Titration question posted by Scott on March 10, 2000 at 14:19:54:

The plasma levels of the drug do not decrease appreciably for 14 hours but in some patients the clinical effect may seem shorter. Generally rather than increase the frequency, I will increase the dosage in my patients. By the way, your oxycontin dose is equivalent to the analgesia of about 3 Percocet 5mg per day. (Percocet has acetaminophen which augments the analgesia of the oxycodone) So you are on a very very low dose...usually I will not use Oxycontin 10mg in my patients because they are more expensive and less effective than 3-4 Percocet 5mg per day.
: Just a quick question for you, I know your busy. I was put on Oxycontin about 2 1/2 months ago.
: Minimum dosage, but now it is not as effective as it was. My questions are:

: HOw long is the actual dosage supposed to last. I have heard both 8, and 12 hours?

: Is it unreasonable for the body to get used to the dosage so fast. I am concerned that my Pain Doctor will
: not respond well when I tell him, at my next visit in 2 weeks. I would really like to up the dosage. I am only
: on 10mg twice a day. No Breakthrough Meds either.

: THanks Very much,

: Scott

• Thanks for the response Scott 00:47:20 3/11/00 (0)