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Posted by Not new, Only Confirms-Gandma Peg on November 08, 2000 at 21:41:57:

In Reply to: Depletion of Creatine Monohydrate in Language delay posted by Lana on November 05, 2000 at 18:44:37:

: On Friday I read about a new study from the U. of Kentucky about the fact creatine monohydrate (heavily researched for neurodegenerative disorders) may help protect against brain injury
: I did a search on creatine monohydrate on Medline and found this abstract that may be of interest to others on this board. The thing to note is that blood examination did not disclose the depletion of carnitine monohydrate!!!
: Ann Neurol 2000 Apr;47(4):511-3
: Reversible brain creatine deficiency in two sisters with normal blood creatine level.
: Bianchi MC, Tosetti M, Fornai F, Alessandri' MG, Cipriani P, De Vito G, Canapicchi R
: Neuroradiology Department, S Chiara Hospital, Pisa, Italy.

: We describe a new creatine metabolism disorder in 2 young sisters who suffered from mental retardation and severe language delay. Blood examination, investigation of the most common neurometabolic disorders, and brain magnetic resonance imaging were normal. Diagnosis was established only by means of in vivo proton magnetic resonance spectroscopy, which disclosed generalized depletion of creatine in the brain. Creatine monohydrate oral administration led to almost complete brain creatine level restoration along with improvement of the patients' disabilities. PMID: 10762163, UI: 20222817

REPLY; This summer, Dr. Ted Paige gave a lecture on creatine levels in autistic kids at a conference of autism topics in Orlando, Fla. I got in touch with his fellow researcher, Dr. Arnie Millar Oct. of 1999.... actually I left a message on his machine and missed his return call. These 2 work at the U.of C. in San Diego. They do creatine testing on a 24 r. urine sample, claiming if the creatine is low, they can correct that and CURE the 'autism'. Yes, I have their phone numbers but I'd like to get the notes from that convention first before starting a riot on this board over 'yet another cure'. Grandma Peg

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