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Old 03-02-2009, 06:39 PM   #4
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Re: Daughter ANA Results

TCJKhon, Hi & welcome. Like the others said, my understanding is that ANA in & of itself does NOT diagnose lupus. For starters, it's positive in a fair number of conditions, not just lupus, like rheumatoid arthritis, Hashimoto's thyroiditis, polymyositis, Sjogren's syndrome, ETC.---so its viewed as only a "threshhold test". Further, it sometimes elevates due to a passing virus, or even to a family tendency. Also, it's possible for ANA to be positive with *no other symptoms* present; that's considered an anomaly, nothing to be worried about.

There are "sticky posts" (permanent info posts) at the top of the thread list. One lists diagnostic criteria, which are a mix of symptoms & tests, skin vs. all other. Mostly you must meet any 4 of the 11 to be dx'ed with *systemic* lupus. But there are lesser kinds. For example, for discoid lupus, you may meet only one or two. For subacute cutaneous lupus, you may meet less than 4 or more than 4; but those tend to NOT include the worst (like kidney & CNS).

If you need to know a LOT more, there are excellent hardcovers in most libraries & bookstores. Look for Dr. Daniel Wallace, or for Dr. Robert Lahita. Both are excellent.

Dr. Wallace writes in his book that he considers 1:1280 to be a high ANA suggestive of a rheumatic condition.

Was your daughter having certain symptoms & problems that led her GP to run the ANA test?

Hard as it is, I think you should try not to worry yourself into a tizzy until you know more. If it does turn out that she has lupus or some "close cousin" (which I hope doesn't happen!), please know that many people do remain pretty mild, with proper Dx, treatment, ongoing care, and sun avoidance. Drop us an update to tell us how you two are making out, when you have time, OK? Sending best wishes to you both, Vee P.S. HANG IN THERE!