Thread: Neuropathy
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Old 04-23-2013, 09:45 AM   #5
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Join Date: Sep 2006
Posts: 1,491
k2626 HB User
Re: Neuropathy

Originally Posted by VeeJ View Post
"k", I think there are several reasons AI's can fail to show up in labs. Some auto-antibodies are hard to detect because they come and go: the immune system misfires & puts out autoantiboies &/or causes general things like inflammation, then the flare recedes. So testing can be like trying to hit a moving target. Timing of labs is important. During my first appt., my rheumatologist remarked, when he saw that I had a brand-new lupus rash starting up, "Good, we're catching it 'on the rise.'"

And in some people, an AI builds steam slowly & can take years to evolve.

Also, some labs are far more proficient at running AI tests than others. Many are titer tests & are notoriously hard to perform accurately.

Another pitfall: were all necessary tests ordered? My sis assured us for 5+ years that "all her labs" were OK. Problem was, he'd never ordered thyroid tests! When he finally did, he dagnsoed her immediately with Hashimoto's thyroiditis and prescribed Synthroid. And for my first two deep-punch skin biopsies, the pathologists only performed microscopic exams of the tissue, omitting step 2, immunofluorescent stain tests, because the dermatologists hadn't ordered the stain tests.

I probably had something like 6-8 sets of AI labs done before positive results showed.

This is out of left field, but can gallbladder problems cause pancreatitis? My sister had multiple mild-ish attacks after certain foods, like peanut butter. Sis still has her gallbladder whereas my mother's was so bad she required surgery.

Do you have any vitamin deficiencies? I had a lot of twitching & neuro-like tingling when my B-12 and Folate were low as part of slow-building lupus. I think various vitamin deficiencies can cause such things. Hugs, Vee

Thanks for your response. Since this all got so bad just in a couple weeks time when I had major stress and never fully went away just in flares-I just can't help but think its AI. One dr Dx me with crest on symptoms alone but I'm one if those that wants the labs!

All vitamins good -so not that

Yes gallbladder can cause pamcreas issues but usually gb stones as far as I know

Also I went into labor at 27 wk with no definite cause who knows maybe related thankfully meds and bedrest kept my baby in

The stabbing burning pains are awful sometimes they even wake me up. Randomly getting it in the wrist this wk