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  • Do PPIs raise Liver Enzymes?

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    Old 11-05-2015, 07:22 AM   #1
    HopefulDoll
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    Do PPIs raise Liver Enzymes?

    I was diagnosed with a hiatial hernia and acid reflux ten years ago and I have been taking a PPI since. In all my blood tests my liver enzymes have been raised. I don't drink alcohol at all and never have, so I'm wondering if it's the meds. I am also on a low dose of citalopram due to surgical menopause.

    Have any of you had this problem with your liver enzymes and what did you do?

    Thanks
    Hopeful

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    Old 11-05-2015, 08:50 AM   #2
    Froodie
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    Re: Do PPIs raise Liver Enzymes?

    I've also been taking PPIs for around 10 years and I recently had a liver function test which showed raised liver enzymes. My doctor sent me for a liver scan which showed non-alcoholic fatty liver (NAFL). I'm now on a diet and I've cut right down on how much PPI I'm taking, on the advice of my doctor. It does say in the patient information leaflet, that raised liver enzymes can be a side effect of taking PPIs.

    Have you had your liver scanned? NAFL is a very common condition.

     
    Old 11-05-2015, 09:58 AM   #3
    HopefulDoll
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    Re: Do PPIs raise Liver Enzymes?

    Thanks for replying Froodie.

    I had a scan a few weeks ago and my liver was said to be normal in size but I don't feel that will last for long!

    What PPI are you on and what dosage?

    What way have you changed your diet? Is weight an issue for you? I have put on a lot of weight since I went into surgical menopause, without eating any more than usual

     
    Old 11-05-2015, 03:55 PM   #4
    rainbowsrock
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    Re: Do PPIs raise Liver Enzymes?

    I have been on Omeprazole for a few years, don't drink and have just been told via a scan that I have the start of fatty liver. My last blood test flagged up liver function too ( I also take a Statin)

    My daughter is 37 and is going through a surgical menopause and is struggling with weight when she wasn't before

     
    Old 11-06-2015, 01:33 AM   #5
    Froodie
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    Re: Do PPIs raise Liver Enzymes?

    I'm reducing my dose of Lansoprazole and currently on 30mg daily. My liver was a normal size but had fatty deposits in it. I had a full hysterectomy last year for cancer.

    I'm on a low carb diet, so I've cut right back on bread, potatoes, rice and pasta. I don't eat things like chocolate, cake, biscuits or crisps. I'm eating a lot of fresh veg and salads, fish and chicken. I'm not drinking fizzy drinks or alcohol.

     
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