It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....

Addison's Disease Message Board

  • Is this normal??????

  • Post New Thread   Closed Thread
    Thread Tools Search this Thread
    Old 09-13-2006, 12:21 PM   #1
    Senior Veteran
    Join Date: Feb 2005
    Location: East Texas
    Posts: 873
    Is this normal??????

    I have hashimoto's thyroiditis and am wondering if my adrenals are stressed or fatigued? My endo did several tests but don't know if he did the correct ones that really tell for sure. I am having trouble increasing my thyroid meds without raising my other words, sensitive to meds. My legs and muscles are weak and I have shortness of breath. Here are the only tests he ran:

    Random cortisol 14.......................Range 2-25

    Then he did the fasting test (don't know the name) where I took the "Dexamethasone" tablet the night before and they drew blood the next morning. That came back: 1 (out of range) ...........Range 2-25 He called it "normal".

    The he did the 24 hr. urine to see if I had adrenal tumor. I did not see my lab reports on that but was told it was normal. Don't even know if that test could have told him if my adrenals were fatigued.

    Now my gp just prescribed Cortef 1 mg morning and 1 mg. night without doing a test first, so I was concerned if I have had the proper test and if I really needed the Cortef. Then I had read somewhere that the saliva test was the only one that was accurate since you test 4 times a day. I would appreciate it if someone could enlighten me on this.

    Sponsors Lightbulb
    Old 09-14-2006, 07:50 AM   #2
    gettin' better
    Senior Member
    gettin' better's Avatar
    Join Date: Aug 2003
    Location: California, USA
    Posts: 142
    gettin' better HB User
    Re: Is this normal??????

    You need an ACTH stimulation test for your adrenals. 1 mg. Cortef is almost nothing -- I can't believe your doctor just prescribed that for no apparent reason. You need to have a talk with him/her and ask just exactly what his diagnosis is and why. Sounds like you may need a good endocrinologist who knows what he'she is doing. Good luck.

    Old 09-14-2006, 08:39 AM   #3
    Senior Veteran
    Join Date: Feb 2005
    Location: East Texas
    Posts: 873
    Re: Is this normal??????

    Gettin' Better.........Is this a more accurate test than the fasting test he did (where I took the Dex pill the night before) and they drew blood the next morning? What is the difference in what each test tells you?

    Old 09-14-2006, 08:48 AM   #4
    Join Date: Feb 2004
    Posts: 342
    WandaB HB User
    Re: Is this normal??????

    Here are the tests you need. The ACTH stim test must be done correctly. You need to get off the Cortef. It is "VERY VERY careless" of your doctor to prescribe this to you with out being diagnosed. The ACTH test is the best way to check for addisons. I don't know anything about the test they did with the Dex. Most docs know nothing about addisons so you will need to tell them what you want done & how it should be done.

    Diagnostic Testing for Addison's Disease

    TEST 1: Electrolyte profile:

    OBJECT: To determine if the patient exhibits a normal serum (blood) sodium and potassium levels.

    THE TEST: A blood draw followed by automated determination of sodium and potassium levels as well as other standard blood markers.

    NORMAL RESULT (will vary somewhat from lab to lab): Sodium 135-150 mEq/L; Potassium 3.5-5.2 mEq/L

    PRIMARY ADDISONIAN: Will show significantly below normal values of sodium and a elevated (above normal) levels of potassium.

    REASON FOR ABNORMALITY: Low or no production of aldosterone from the adrenal cortex. This steroidal hormone regulates our mineral balance and is called a mineralocorticoid. Primary Addisonians lose sodium and retain potassium. Abnormal values here, in additon to physical signs and symptoms, require the next test.

    TEST 2: The ACTH stimulation test:

    OBJECT: To determine if the patient's adrenal glands can respond to the ACTH message from the pituitary to increase cortisol production in the adrenal cortex.

    THE TEST: The test is usually given first thing in the morning when normal cortisol levels are highest. Blood is withdrawn from the patient to establish a baseline (No instructions regarding necessity for fasting). The patient is given 250 micrograms (ug) of ACTH (Cortrosyn, Cosyntropin, or Synacthen) by injection in saline at one time. Blood is drawn at 30 minutes and/or 60 minutes and the serum cortisol level is determined.

    NORMAL RESULTS: Normal pre-injection levels of cortisol are 5-25 ug/dL (138-690 nmol/L). The value should double at 30-60 minutes with a minimum of 20 ug/dL (552 nmol/L). PRIMARY ADDISONIAN: There will be no or little increase in cortisol levels upon ACTH injection. Notes: It is stated in several places that a single test of cortisol levels, or even 24 h urinary levels of cortisol and its metabolites, are NOT DIAGNOSTIC! In the normal individual cortisol levels are seen to pulse. Low cortisol production in either the serum or the urine after ACTH stimulation is diagnostic of Addisons disease.

    SECONDARY ADDISONIAN (Pituitary malfunction): Low cortisol production can be seen if the patient has "functional adrenal cortical atrophy" due to prolonged absence of normal ACTH secretion. This type of patient would not show the typical hyper-pigmentation of primary Addisons.

    REASON FOR ABNORMALITY: Due to autoimmune, or other destruction of enzymatic (biocatalytic) machinery of the adrenal gland, there is no response to ACTH and no production of cortisol and other adrenal steroids necessary for life. If this test gives normal results and the patient has other signs and symptoms then one of the following tests is required.

    Old 09-14-2006, 11:52 AM   #5
    Senior Veteran
    Join Date: Feb 2005
    Location: East Texas
    Posts: 873
    Re: Is this normal??????

    Thanks for all the info. Can you just have stressed or fatiqued adrenals (meaning a temporary condition) and it not be Addison's (which to me, if I understand correctly is a permanent condition)?

    I have been hypo for 30 yrs and have been taking 2 grains of Thyrolar for most of that time and haven't had any symptoms and felt fine. A new doctor (3 yrs ago) checked my thyroid in order to get my prescription renewed. My TSH was like .54 (not out of range) and my T4 was in top 1/3 of range (not out of range). He didn't check my Free T's so I can just imanage it would have been even lower. He cut my meds in half and put me on Synthroid. Within a few months I could hardly walk. I went to another dr. and had labs done and my FT4 was below the range. During that time I was also under a lot of stress and I just figured cutting meds so drastically, taking away all of my T3 by changing brands, and the stress I was under just had to stress my adrenals and I have never been the same since. Can't get my levels back up to where they should be without being sensitive to meds causing bp to rise and TSH suppressed. My TSH has NEVER been more than 1.3 even when I was severely hypo.

    Any input on my situation would be much appreciated.


    Closed Thread

    Related Topics
    Thread Thread Starter Board Replies Last Post
    Low end of normal but all symptoms, is dr wrong? andeflora Thyroid Disorders 15 12-12-2011 01:56 PM
    Normal Lab Work comes back with 125 Liver Enzyme manchak99 Liver & Pancreas Disorders 3 04-23-2010 02:53 PM
    Three days post op....feeling this normal?? WVPeach Thyroid Disorders 2 04-20-2010 01:26 PM
    bruising ater injection is it normal???? dinnon Hepatitis 3 04-19-2010 06:55 AM
    Doctor says labs are normal- are they? macs4life06 Thyroid Disorders 10 02-04-2009 04:11 PM
    Lab results - Dr. says they are normal love2fish Thyroid Disorders 9 06-16-2008 08:34 AM
    I think these results are normal....I wish I had something to BLAME this on! hopalong_too Thyroid Disorders 6 08-22-2007 10:49 PM
    "Normal" Test Results SRSFLA Thyroid Disorders 5 10-31-2006 08:25 AM
    Various Numbers, What's Normal? Man of Iron Diabetes 1 07-16-2005 08:37 PM

    Thread Tools Search this Thread
    Search this Thread:

    Advanced Search

    Posting Rules
    You may not post new threads
    You may not post replies
    You may not post attachments
    You may not edit your posts

    BB code is On
    Smilies are On
    [IMG] code is Off
    HTML code is Off
    Trackbacks are Off
    Pingbacks are Off
    Refbacks are Off

    Sign Up Today!

    Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

    I want my free account

    All times are GMT -7. The time now is 11:36 AM.

    © 2020 MH Sub I, LLC dba Internet Brands. All rights reserved.
    Do not copy or redistribute in any form!