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Addison's Disease Message Board

Cortef Resistance

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Old 10-12-2012, 10:07 AM   #1
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Join Date: Jan 2008
Location: Red Bluff, Ca USA
Posts: 10
susan1952 HB User
Question Cortef Resistance

My Cortisol Serum results have been dropping while on 30 mg Cortef taken
15mg at waking, 10 mg at 10 am, 5 mg at 3pm. I was having to bump up almost daily. My last test results dropped to below normal and my Endo increased my baseline to 40 mg and told I was resistant to Cortef. I was
given the emergency procedures again with a 2 month follow up. I don't feel that the increase dose is making a difference. My primary physician says I physically present looking like Cushings side effects, yet below normal cortisol levels and wants me to talk to Endo about referral to Mayo Clinic or other teaching hospital. Pretty scared! Any advise

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