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Axiron requires additional Hydrocortisone

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Old 11-18-2012, 01:51 PM   #1
Join Date: Oct 2012
Posts: 3
hwbags HB User
Axiron requires additional Hydrocortisone

This is a followup to a previous post. It is long and I appreciate you reading and replying
To review: I have had Addison's disease for 45 years and it has thankfully been very well controlled for almost that entire time.
Follwing major surgery my low tesosterone dropped to almost No testosterone.
The endocrinologist convinced me to try androgel and it helped my recovery.
I was able to comfortably survive on my 25-35 mg dose of hydrocortisone and I gradually gained strenth that I lost after 3 surgeries.
This took about a year. Following a trip to Alaska (where I felt young and vigorous even though I missed a few doses of Androgel)
I started to again have problems.
This was akin to the post surgical era without Androgel and I needed up to 60 mg of Hydrocortisone to feel just reasonable.

Becasue of pretty serious acne my endocrinologist switched me to Axiron and my problems wiith hydorocortisone continued.
The acne mostly went away. So it has been months now and I have given up Halcion/Zoloft and most Cafeine searching for a solution.
I suspected that these were contributing to the problems with Hydrocortisone.
I finally tried cutting my Axiron in half and I was able to get back to the more reasonable dosage of Hydrocrotisone.
Now again back at 60 mg I am back to suffering. It has helped a little to stagger two 30 mg Axiron doses by several hours. I read the product description ans suspected that the impulse in serum Testosterone is doing something to me.
A 70% increase in Serum testosterone in two hours after application. This is not exactly a time released medication.

If anybody has an explanation or even a theory for this increased Hydrocortsone requirement I would love to hear from you
Cutting my Axiron is half (to lower my hydrocortisone requirment) may be the only solution.
It is also undesireable since I defintily feel a difference at least when I am at the gym.
This observation is too bizarre but to be scientific I have to include it. The night before my blood was to be tested by the endocrinologist I had to fast overnight and planned to go in a state of Addison's defficiency. However to survive my gym workout before the blood test I ate a late night, hardy, and salty "fast food" meal, greatly deviating from my cave man diet which has very few carbs. Here's the problem: I was OK, at least when I had my blood tested and for most of that day. I need a long term solution that does not involve fast food.

Again Thanks in Advance

Last edited by Administrator; 11-18-2012 at 09:50 PM.

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