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Antihistamines & Depression

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Old 05-21-2002, 08:01 AM   #1
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Join Date: May 2002
Location: St. Albans, Herts, UK
Posts: 142
girlwondering HB User
Arrow Antihistamines & Depression

Has anyone noted any correlation between antihistamines and depression?

I have been on antihistamines forever (it seems)--mostly Allegra, but also Zyrtec and Claritin. For about a week I was able to go WITHOUT (any) and felt emotionally better, nearly instantly. Now, looking on the net, I see that there is some correlation.

Has anyone else notieced this?

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Old 05-21-2002, 08:59 PM   #2
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Join Date: Apr 2002
Location: California
Posts: 264
RedeemedHeart HB User

Yes, If I take Benadryl for more than two or three days in a row I get depressed. When I stop it goes away overnight. I noticed this by accident several years ago.
I don't know why it does that.

Old 05-31-2002, 11:26 AM   #3
Join Date: May 2002
Location: England
Posts: 81
DeeJay HB User

I have been taking Anti-Histamines for years and can't say I have noticed this. In fact, I get depressed when i don't take them cos I my symptoms (allergic rashes/itching) go mad!! I have tried Clarityn, Zirtek, telfast the lot - I worry about the long term effects of taking any drug though. I find that Clarityn and Zirtek are pretty inoffensive and apart from the active ingredient shouldn't cause any reactions like depression - though who knows.
~~Stick 'em up punk it's da Fun Lovin' Criminal~~

Old 05-12-2003, 12:29 PM   #4
Join Date: May 2003
Posts: 1
json11 HB User

I noticed after taking allegra that I became quite depressed and I didn't know why. The only major change was that I had started taking allegra for allergies. Yes they worked wonders for my allergies but not for the side effects. The minute I stopped taking it I felt much better.

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