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Strawbaby 11-03-2008 04:23 AM

Morphine & Respiratory Depression
My husband has recently begun having respiratory problems. It was determined that the oxygen in his blood is very low. I understand that 95/100is a good reading and anything in the 80's is troublesome. He had a test with the little finger thingy while sleeping and his dropped to 62...the test was redone and a day later a big oxygen machine delivered to our home with the instructions to use it at night. I don't know what that second reading showed. He's been on the oxygen about a week. A few weeks prior he was put on a different breathing machine that he uses every 8 hours. It's used with a medicine called Ipratropium and Albuterol. This was prescribed due to very heavy wheezing. So far the wheezing hasn't gotten any better. He's still also using that machine.

His history is several back surgeries including a fusion January 2006. It's believed he has arachnoiditis. He's on lots of medication for severe nerve pain. My question...........have any of you experienced respiratory problems after two to three years on morphine and/or the other pain medication so common to this condition? My extensive reading and research shows that respiratory depression is a side effect of morphone use but I didn't think it would happen this soon. Somehow, I thought that was years down the road. What happens now? Will this get better? His dosage of morphine was recently increased due to the increase in pain, but the respiratory problems were already happening before the increase.

I keep looking for things to get better for him but it keeps getting worse. Now this big ol' breathing machine really has me worried. Is this temporary? Do any of you have any experience with this?

I appreciate this message board. I come here often and learn a lot.


Executor 11-03-2008 07:10 AM

Re: Morphine & Respiratory Depression
Hello, and I'm sorry that your husband is having problems. As a general rule, any narcotic can bring on the side effects you describe. All narcotics are "depressants", thus, why they are sedating in nature. They slow down all bodily functions...Metabolism, breathing, digestive system, can cause ED in men, and etc.

Some people do experience a "paradoxical" effect, or opposite, and this is why some abuse them. The paradoxical effect is also why "like treats like" or why they give ADHD patients stimulants. In most patients, however, narcotics are more depressive in nature.

As far as morphine being worse than the others in terms of oxygen, I do not know. I do know that morphine can be more sedating in nature than some others. I would circle back and ask your Doc. Your pharmacist is also a great source of information, especially so because he/she has all the information re: all the meds your husband is on and the cumulative effect is important.

As far as your increase, the body will normally adjust in regards to it's normal functions (such as digestive and constipation for example). If your Doc gave him an increase, then he must feel it's ok. However, if you think his breathing is an issue, I would definitely bring it up. There are many other meds at your Doc's disposal. Pain mgt is a very individualized field...What works for one may not work for another. Additionally, it's not unusual for it to take a while to get everything dialed in correctly.

Take care, and good luck,


tiggertoo2174 11-03-2008 08:41 AM

Re: Morphine & Respiratory Depression
I would talk to the Dr. about what he/she thinks the cause of the respiratory distress is. If your husband has been on morphine for 2-3 years it's unlikely that the morphine alone is responsible. I've heard of opiates depressing respiration but that is generally considered to be slower shallower breaths. The wheezing would indicate some other type of respiratory problem, the first things that come to mind are asthma and bronchitis. Check with the Dr., you need to know what type of respiratory problem your husband is dealing with.


Strawbaby 11-03-2008 09:17 AM

Re: Morphine & Respiratory Depression
Thanks Executor and Tigger for your replies. Actually, asthma and bronchitis have been ruled out. The wheezing happens on the exhale instead of inhale. It has been determined he has a narrow bronchial tube and he is also bothered by acid reflux which may have some impact on the wheezing. I guess my biggest concern is the low oygen.......I'm not even sure the wheezing and low oxygen are connected. He's scheduled for a sleep study in a couple of weeks.

He was a healthy, hard working, active man until June 2005 when he sneezed and herniated a disc. It's been downhill ever since. He just turned 60. We just can't get used to him deteriorating so fast. This breathing thing really has me worried. We'll be seeing the doctor again soon and maybe she'll have some updates for us.


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