View Full Version : Switching Meds for UC

01-06-2016, 12:32 PM
I have been posting here lately, trying to get through a terrible flare. Since I was diagnosed with UC in 1998, I have taken Asacol, then switched to Delzicol. These are both mesalamine meds. I have also taken Canasa suppositories, and oral prednisone. All of these work less and less to maintain remission and also overcome a flare. Are there meds to try in terms of 'next line of defense' or does it differ depending on flare severity, number of years with UC, someone's age, etc? In other words, would my next options be to try sulfasalazine meds before trying immunosuppressant drugs, or do some people need to go right to the stronger drugs for a bad flare? Just trying to get my thoughts in order before my GI visit next week. I am concerned that she is not being aggressive enough in my treatment, but at the same time I don't want to jump into anything too quickly. She has me taking Delzicol and then Canasa suppositories. Neither works. Aren't they pretty much one and the same? I want to question her on taking either pred suppositories or enemas instead of Canasa. These were effective for me a long time ago. This stuff can really drive you crazy.

02-15-2016, 11:44 AM
Hi...sorry for the late reply. How are you doing at this point, and what meds has your doctor put you on now?

I would strongly suggest to try the Rowasa mesalamine retention enemas and if they're not working as well as you'd like, you can support them with a foam steroid enema to use during the day.

Where exactly is the extent of your UC...limited or throughout?

Are you on pred at this time?