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  • Methotrexate and long term use

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    Old 01-22-2009, 03:30 PM   #1
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    Methotrexate and long term use

    Hi everyone,

    I started methotrexate over a month ago because the plaquenil I have been on for over a year seemed to stop working for my joint pain. After trying several NSAIDS, my rheumie put me on low dose prednisone and added the methotrexate.

    I've read that methotrexate may not be good to take for the long term. Has anyone heard this? Is there any other DMARD that can be taken for years besides the plaquenil? Also, I have been experiencing issues with major fatigue. The day after I take it I am wiped out and weak, like I am getting over the flu. It seems like you have to trade one problem for another....

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