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  • curious if this resembles autoimmune hepatitis

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    Old 09-07-2015, 10:09 AM   #1
    venchenza84's Avatar
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    venchenza84 HB User
    curious if this resembles autoimmune hepatitis

    weird anemia with low rbc, normal hemoglobin, hemacrit, platelets. High mcv and mch. Normal mchc. macornodular cirrhosis in the left lobe and bridging fibrosis on other parts of liver. Hashimotos thyroiditis. high igg over 2200mg and high igg4 at 237 mg.

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    Old 09-15-2015, 07:18 AM   #2
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    Re: curious ift his resembles autoimmune hepatitis

    Hi. I'm so sorry you're in a state of worry. From what I've read, there is no single test for autoimmune hepatitis (AIH). Below is how I understand the approach for dxing AIH.

    First goal is excluding causes OTHER than AIH, like fatty liver, alcohol abuse, drug-induced liver damage, and the VIRAL forms of hepatitis (Hep A, Hep B, and Hep C). I do not know whether Hashimoto's can affect liver (sorry).

    Then, for AIH, tests for specific markers typically are done:
    • What's called Type 1 AIH is most common in US. Key tests are ANA (antinuclear antibody) and Anti-smooth muscle antibody (ASMA).
    • What's called Type 2 AIH is most common in Europe. Key tests are anti-liver kidney microsomal antibody type 1 (anti-LKM1) and anti-liver cytosol type 1 (anti-LC-1).

    Bottom line: I don't think you can know yet, without further testing and history-taking. I think first step is finding out whether your liver abnormalities could be explained by causes OTHER than AIH. Next step: tests for autoantibodies seen in AIH. Keep in touch, OK? With warm wishes & hugs.

    Last edited by VeeJ; 09-15-2015 at 07:21 AM. Reason: clarify last paragraph

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