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Lupus vs Malignancy ???

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Old 03-30-2012, 03:22 AM   #1
Join Date: Mar 2012
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Lupus vs Malignancy ???

Ok I'm a 38yo F. Presented with pain, edema and numbness to Right lower extremity and severe fatigue. Dvt ruled out. My Dr had no explanation for my symptoms and stated my labs were fine except my platelets were slightly elevated. After 3 days my right leg was back to normal. 3 weeks later symptoms reappear but in left leg. Disgruntled with my first Dr. I made an appt with a new Dr. He immediately prescribed prednisone and ordered an ESR which was elevated, he then ordered a CRP and ANAwhich werealso elevated. Next a MRIof my head . MRI detected signal anomalies in cervical bonemarrow.Now I'm waiting fora bone marrow biopsy. I have tried to research these symptoms and come up with nothing. Any help would be appreciated.

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Old 03-30-2012, 06:08 AM   #2
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Re: Lupus vs Malignancy ???

You don't mention how high your ANA screening titre was, nor it's pattern. You also didn't mention if your sed rate was really high or just elevated. Lupus is not the only thing that can cause an elevated ANA titre, and it may not mean anything is wrong. And from what I can see, the signal anomaly can be nothing or again, a variety of things. Do you have other symptoms other than the 2 episodes of edema? How long have you been experiencing fatigue? The various autoimmune diseases are usually diagnosed by symptoms, as well as, or in spite of labs. That's why it oftimes takes a long time to diagnose them. Wishing you all the best.

Last edited by luca689; 03-30-2012 at 06:10 AM. Reason: forgot something

Old 03-31-2012, 05:52 AM   #3
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Re: Lupus vs Malignancy ???

Interesting? My presenting symptoms were also swelling, pitting oedema, pain, numbness in my right foot/ankle. My podiatrist insisted i see my general practitioner straight away. My general practitioner told me that i did not have pitted oedema despite the fact that his fingers marks were still clearly depressed on my skin ! I have been on anti-inflammatories for months awaiting rheumatoid appointment. ANA is positive 1/160 speckled pattern. I have a lot more symptoms than just the lower extremity issue, but the foot has NEVER really improved and i have not been able to walk for more than 10 minutes for months without considerable pain.

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