Tanning pills typically contain the pigment canthaxanthin. Although the FDA has approved the use of canthaxanthin as a color additive in food, it has not approved its use as a tanning agent. Much larger quantities of canthaxanthin than the amount used as a food coloring must be ingested to change skin color. After canthaxanthin is consumed, it is deposited throughout the body, including in the skin, which turns an orange-brown color, and also the internal organs (liver, brain, etc.). Canthaxanthin-based tanning pills have been linked to dangerous side effects, including hepatitis (inflammation of the liver) and canthaxanthin retinopathy (formation of yellow deposits in the retina of the eye).
Source: [url="http://chemistry.about.com/library/weekly/aa022602a.htm"]http://chemistry.about.com/library/weekly/aa022602a.htm[/url]
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