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Trileptal Muscle Twitching

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Old 04-12-2011, 04:12 PM   #1
Join Date: Apr 2011
Location: WA state, USA
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Trileptal Muscle Twitching

Hello All,

My name is Angela, and I was just diagnosed with bipolar disorder 2 months ago. The only med combination I have tried so far is Trileptal, Celexa, and Saphris. My current meds are: 900 mg. Trileptal, 40 mg. Celexa, and 5 mg. Saphris. I am also taking omeprazole for GERD symptoms, Zyrtec for allergies, and metoprolol tartrate for high blood pressure/anxiety.

Typing in "trileptal muscle twitching" on Google led me to this board, where there was an old thread about this, now closed. For the past week, especially for the past 3 days, I have been experiencing increasing muscle twitching. Most of this is occuring in my calves, upper legs, and feet. However, I have also experienced this in my back, abdomen, arms, hands, and some in my chest. Sometimes I have painful cramping as well.

I have been doing a little bit of research on muscle twitching and chest pain, and I've found that a lot of these problems can be caused by anxiety. I have a fairly high level of anxiety, and I am still getting adjusted to not feeling so bipolar anymore. My symptoms have increased the past few days, and I've been on Trileptal since March 2nd, though I have been on the 900 mg. dose for about a week. My doc and I have been tinkering with the Trileptal dosage the past couple of weeks because I thought it was causing some of my anxiety. Does anyone here think that my Trileptal could be causing some of my muscle twitching/spasms? I just got a blood sodium test done today, and I have also been a hypochondriac my whole life. Do you think it's anxiety/tension, which I've had a ton of lately, or medication related? Thanks for any input!

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Old 04-13-2011, 03:26 PM   #2
apples of youth
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Re: Trileptal Muscle Twitching

I have been on a combination of Trileptal and Effexor XR for awhile. As soon as I started taking Effexor I got these awful...I guess you'd call them brain spasms? It was like a jolt of electricity straight to my skull. And about a year after taking Trileptal, I started getting really bad twitching. For me it is mostly when I'm trying to relax or fall asleep. It's like my body is trying to adjust from being paranoid and anxiety ridden all day to a much more calmed down state. My twitching is usually in my upper body (neck, shoulders, arms, etc..), but there are times when I get it in my legs and feet as well.

I had my dosage changed to about twice as much and that's when the twitching started happening and then it's been getting worse since I've been taking an even bigger dosage these days. So, it definitely seems like Trileptal could be the case, but stress is also a big factor to consider as well. I think it's more than likely a combination of both.

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