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IBS and restless legs - HELP !


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Old 11-17-2005, 02:06 PM   #1
stubs
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IBS and restless legs - HELP !

Ive got IBS and take the usual Mebeverin. When the IBS kicks off, so does the restless legs. Im spending hours in the bathroom every night. The IBS I could live with - if it was just IBS, but the restless, twitching legs keep me awake more than the IBS - does this 'two for the price of one' thing ring any bells for anyone and if so what can I do - getting desperate and very, very,very tired !

 
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Old 11-17-2005, 04:41 PM   #2
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Re: IBS and restless legs - HELP !

Hey, I know that they give Klonopin, a "benzo" anti-anxiety med for restless leg syndrome. It might actually help the IBS, too... becuase it's the only benzo that actually might decrease the release of seretonin.


So you might be able to kill two birds with one stone... the Klonopin might really help the restless legs, and the IBS.

 
Old 11-18-2005, 01:50 PM   #3
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Re: IBS and restless legs - HELP !

thanks ! I trhought that seretonin was one of the good guys though ?

 
Old 11-18-2005, 03:24 PM   #4
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Re: IBS and restless legs - HELP !

in depression.

thats why when it blocks the seretonin, its not as helpful for depression.

anti-depressants like prozac act as a neuromodulator in that it prevents the enzyme from breaking down serotonin.

95% of the serotonin in one's body is found in the cells lining the intestines. there are different receptor sites that act as accelerators, and brakes. namely, the 5ht3 and 5ht4 sites.

blocking the serotonin released can have a direct relaxant effect in the intestines.. and klonopin is the only anti-anxiety med that has the potential to do this.

 
Old 11-19-2005, 11:46 AM   #5
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Re: IBS and restless legs - HELP !

thanks - Thats really intriguing - there seems to be an element of seretonin being a double edged sword then - if IBS is a symptom of stress and anxiety..the latter often tipping over into depression, dont you need to keep the seretonin levels up via one of the selective seretonin uptake inhibitors. or is it one of these finely tuned balance situations !

 
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