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High Alkaline Phosphatase (ALP) Indicates Possible Colorectal Cancer (CRC)?

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Old 07-30-2012, 07:44 PM   #1
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High Alkaline Phosphatase (ALP) Indicates Possible Colorectal Cancer (CRC)?

My aunt's alkaline phosphatase (ALP) is around 300 the last two times tested. Her ALT and AST are also bit elevated (~50) but her GTT is normal. She has chronic HBV and is being treated by a hepatologist and her virus levels are considered undetectable.

After seeing ALP elevation twice in a row, the hepatologist wrote a note to our PCP to follow up for high ALP. She thought it was possible that it could be due to non-liver sources, specifically, possible colorectal cancer (with liver metastasis) or bone related disorder (Paget's, e.g.). Did anyone who contract CRC notice very high ALPs around 300? Her ALP was always a bit high (150-200) but not as high as now. We're seeing the PCP this Fri but want to line up possible Gastroenterologist since it takes quite a while to find one in our area. She thinks it's probably not bone-related (bone cancer) since ethnically she's Asian (rare to have high AP for such causes for Asians, supposedly).

Just how high is too high for ALP? 300? 500? Thanks.

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