It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Cancer: Prostate Message Board

  • my PSA rise after doing radiation therapy one year ago.

  • Post New Thread   Reply Reply
    Thread Tools Search this Thread
    Old 01-17-2020, 10:45 AM   #1
    efang
    Senior Veteran
    (male)
     
    Join Date: Sep 2003
    Location: Rockville, MD
    Posts: 511
    efang HB User
    my PSA rise after doing radiation therapy one year ago.

    I did Rediation therapy on end of 2018, now my PSA changed as following list:
    Date
    date PSA Testosterone
    6/28/18 3.87
    12/2018 did radiation therapy
    1/14/19 3.80 434
    3/23/19 2.60 411
    6/22/19 1.16 345
    9/28/19 0.88 361
    1/11/20 1.36 382


    The 1/11/20 PSA started to rise, I saw my radiation oncologist doctor yesterday , he said this rising can be “ benign PSA bounce”, there are 30-40% of his patents had same experience, but he said if I got three time consecutive rising , he will re- concern this and checks my prostate.
    I noticed that on 9/28/19 the PSA started to decrease slowly. I will do my next test in three months not six months , but my doctor asked me to see him in six months.
    Please let me know your opinion, thank.
    __________________
    treated prostate cancer by SBRT on 12/2018 PSA. 3.80, 2.60 , 1.16 , 0.88 , 1.36 , 0.50。 HBAiC around 6.0.

     
    Reply With Quote
    Sponsors Lightbulb
       
    Old 01-17-2020, 08:55 PM   #2
    ASAdvocate
    Senior Member
    (male)
     
    Join Date: Dec 2019
    Location: Alexandria, VA USA
    Posts: 101
    ASAdvocate HB UserASAdvocate HB UserASAdvocate HB UserASAdvocate HB User
    Re: my PSA rise after doing rediation therapy on one year ago.

    Quote:
    Originally Posted by efang View Post
    I did Rediation therapy on end of 2018, now my PSA changed as following list:
    Date
    date PSA Testosterone
    6/28/18 3.87
    12/2018 did radiation therapy
    1/14/19 3.80 434
    3/23/19 2.60 411
    6/22/19 1.16 345
    9/28/19 0.88 361
    1/11/20 1.36 382


    The 1/11/20 PSA started to rise, I saw my radiation oncologist doctor yesterday , he said this rising can be “ benign PSA bounce”, there are 30-40% of his patents had same experience, but he said if I got three time consecutive rising , he will re- concern this and checks my prostate.
    I noticed that on 9/28/19 the PSA started to decrease slowly. I will do my next test in three months not six months , but my doctor asked me to see him in six months.
    Please let me know your opinion, thank.
    That’s correct. After primary RT, the PSA can bounce around for up to three years,

    Usually, the standard I see cited is “nadir + 2” before there is recurrence. That would mean that 2.88 is your trouble trigger.

    Your doctor is following the standard protocol.

     
    Reply With Quote
    Old 01-18-2020, 05:37 AM   #3
    efang
    Senior Veteran
    (male)
     
    Join Date: Sep 2003
    Location: Rockville, MD
    Posts: 511
    efang HB User
    Re: my PSA rise after doing rediation therapy on one year ago.

    Quote:
    Originally Posted by ASAdvocate View Post
    That’s correct. After primary RT, the PSA can bounce around for up to three years,

    Usually, the standard I see cited is “nadir + 2” before there is recurrence. That would mean that 2.88 is your trouble trigger.

    Your doctor is following the standard protocol.
    Yes, I asked my doctor about "nadir+2", he just said if I got three times rising in consecutive test, he will concern to check my prostate .

    Thanks,
    __________________
    treated prostate cancer by SBRT on 12/2018 PSA. 3.80, 2.60 , 1.16 , 0.88 , 1.36 , 0.50。 HBAiC around 6.0.

     
    Reply With Quote
    Old 01-18-2020, 09:29 AM   #4
    Terry G
    Junior Member
    (male)
     
    Join Date: Dec 2019
    Location: Butler PA
    Posts: 30
    Terry G HB User
    Re: my PSA rise after doing radiation therapy one year ago.

    I’m new to this board coming over from a sister board. Regarding rising PSA following RT there is a lot of sound data suggesting it can be a good thing. See ‘PSA Bounce After Radiotherapy’ on ASCOPOST.COM or ‘Love Your Bounces’ on The New Prostate Cancer Infolink. With all PC treatments regular monitoring of PSA is just part of the process. Bounces can typically occur 15 to 40 months following RT treatment when radiation is used as a mono therapy. My RO says he sees bounces on 25 to 35% of patients. He also reminds me that PC is a marathon and not a sprint. For those selecting surgery a bounce even a small one is a reason to be concerned. I’m glad we both have found this board since the information contained is excellent.
    __________________
    Rising PSA:
    11/13 1.95; 9/15 3.28; 10/16 5.94
    TRUS 1/17
    Bx: Three of twelve cores adenocarcinoma Gleason 6 (3+3) all on left side, no pni.
    DOB 7/21/47; good health; age 69 @ Dx
    Treated 6/17 SBRT @ Cleveland Clinic by Dr. Tendulkar
    Reduced ejaculate only side effect; everything works
    To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

    PSA’s post.SBRT 1.1, 1.1, .9, 1.8, 2.7, 1.0, 0.3

     
    Reply With Quote
    Old 06-25-2020, 12:15 PM   #5
    efang
    Senior Veteran
    (male)
     
    Join Date: Sep 2003
    Location: Rockville, MD
    Posts: 511
    efang HB User
    Re: my PSA rise after doing radiation therapy one year ago.

    I just did a PSA test on 6/23 /20, my PSA dropped down to 0.50 , so I think
    my doctor will be satisfied this time. thanks.
    __________________
    treated prostate cancer by SBRT on 12/2018 PSA. 3.80, 2.60 , 1.16 , 0.88 , 1.36 , 0.50。 HBAiC around 6.0.

     
    Reply With Quote
    The following user gives a hug of support to efang:
    IADT3since2000 (06-27-2020)
    Old 06-25-2020, 05:26 PM   #6
    Terry G
    Junior Member
    (male)
     
    Join Date: Dec 2019
    Location: Butler PA
    Posts: 30
    Terry G HB User
    Re: my PSA rise after doing radiation therapy one year ago.

    efang,
    Nice drop, looks like a typical bounce. As I mentioned earlier guys with a bounce seem to have better long term results. We’re never completely free of regular PSA checks so wishing you low numbers down the road.
    __________________
    Rising PSA:
    11/13 1.95; 9/15 3.28; 10/16 5.94
    TRUS 1/17
    Bx: Three of twelve cores adenocarcinoma Gleason 6 (3+3) all on left side, no pni.
    DOB 7/21/47; good health; age 69 @ Dx
    Treated 6/17 SBRT @ Cleveland Clinic by Dr. Tendulkar
    Reduced ejaculate only side effect; everything works
    To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

    PSA’s post.SBRT 1.1, 1.1, .9, 1.8, 2.7, 1.0, 0.3

     
    Reply With Quote
    Old 06-29-2020, 02:31 PM   #7
    noonereal
    Newbie
     
    noonereal's Avatar
     
    Join Date: Jun 2020
    Location: Goshen
    Posts: 4
    noonereal HB User
    Re: my PSA rise after doing radiation therapy one year ago.

    Just got my 1st PSA 6 months post radiation and ADT.

    It is .40.

    6 months ago when the therapies were first finished it was .06.

    I am not sure what to make of it.

    Anyone????

     
    Reply With Quote
    Old 06-30-2020, 05:06 AM   #8
    IADT3since2000
    Senior Veteran
    (male)
     
    Join Date: Nov 2007
    Location: Annandale, VA, USA
    Posts: 2,507
    IADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB User
    Re: my PSA rise after doing radiation therapy one year ago.

    Hi noonereal,

    It is typical for PSA to rise, a bit, after cessation of ADT and consequent recovery of testosterone. The rise you are seeing could well be that.

    There is also a common phenomenon known as "PSA bounce" after radiation, but I suspect your increase is more related to recovery of testosterone.

    ….Jim

    - - - - - - - - - - - - - - - - - - - - - - - -
    Diagnosis Dec 1999 PSA 113.6 (first ever), age 56
    Gleason 4+3=7 (J. Epstein, JHU), all cores +, most 100%; "rock hard" prostate with ECE - stage 3, PNI, PSADT determined later 3-4 months; technetium bone scan and CT scan negative; prognosis 5 years.
    Later ProstaScint scan negative except for one suspicious small area in an unlikely location. ADT Lupron as first therapy, in Dec 1999, then + Casodex in March 2000, then + Proscar and Fosamax in Sep 2000. Rejected for surgery January 2000; offered radiation but told success odds were low; switched to ADT only vice radiation in May 2000, betting on holding the fort for improved technology; PSA gradual decline to <0.01 May 2002. Commenced intermittent ADT3 (IADT3) with first vacation from Lupron & Casodex. Negative advanced scans in 2011 (NaF18 PET/CT for bone) and 2012 (Feraheme USPIO for nodes and soft tissue). With improved technology, tried TomoTherapy RT, 39 sessions, in early 2013, plus ADT 3 in support for 18 months (fourth round of IADT3), ended April 2014. Continuing with Avodart as anti-recurrence shield. Current PSA remarkably low and stable at <0.01; apparently cured. (Current T 99 6/5/20.) Supportive diet/nutrition, exercise, supportive medications during this journey, as well as switches in antiandrogen, 5-ARI, and bone drugs.

     
    Reply With Quote
    The Following User Says Thank You to IADT3since2000 For This Useful Post:
    noonereal (06-30-2020)
    Old 07-07-2020, 11:54 AM   #9
    noonereal
    Newbie
     
    noonereal's Avatar
     
    Join Date: Jun 2020
    Location: Goshen
    Posts: 4
    noonereal HB User
    Re: my PSA rise after doing radiation therapy one year ago.

    My doctor called it concerning and will test me again in a couple months instead of the standard 6 month check.

     
    Reply With Quote
    Reply Reply

    Related Topics
    Thread Thread Starter Board Replies Last Post
    Benign Prostate Enlargement (BPH), PSA and Prostate Cancer: When to Biopsy? IADT3since2000 Cancer: Prostate 12 01-07-2020 09:51 AM
    Radio Therapy helgi Cancer: Prostate 7 08-14-2019 01:00 PM
    Going from incurable to likely curable!!! (Yarbo3) yarbo3 Cancer: Prostate 50 12-09-2011 07:41 PM
    Going from incurable to likely curable!!! IADT3since2000 Cancer: Prostate 26 10-23-2011 03:12 PM




    Thread Tools Search this Thread
    Search this Thread:

    Advanced Search

    Posting Rules
    You may not post new threads
    You may not post replies
    You may not post attachments
    You may not edit your posts

    BB code is On
    Smilies are On
    [IMG] code is Off
    HTML code is Off
    Trackbacks are Off
    Pingbacks are Off
    Refbacks are Off




    Sign Up Today!

    Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

    I want my free account

    All times are GMT -7. The time now is 09:55 PM.





    © 2020 MH Sub I, LLC dba Internet Brands. All rights reserved.
    Do not copy or redistribute in any form!