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  • Rising PSA

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    Old 07-21-2020, 11:56 AM   #1
    xxsm's Avatar
    Join Date: Oct 2015
    Posts: 2
    xxsm HB User
    Rising PSA

    Hello All..

    I don't have all numbers but what I do have is... My husband had prostate removal 6 six years ago. First year bloodwork undetectable 2nd year higher and he did radiation. His last 2 numbers were .07 then last week .11. He is now being referred back to oncologist. From my reading on the subject this means there is still PSA cells left behind. We are scared as my husband is only 53.
    Has anyone been through this and may know what would be the next step?

    Thanks for letting me vent.

    worried wife.

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    Old 07-21-2020, 03:32 PM   #2
    Join Date: Dec 2019
    Location: NJ
    Posts: 68
    Steve135 HB User
    Re: Rising PSA

    xxsm, unfortunately too many of us have gone through this several times. Lets just see what the next testings brings lots of things affect the PSA test from who's doing it to what you eat. If you was on a bike or horse, or sex! Where you get the test done (Same Place) Lets not jump the gun just yet. Plenty of contributors will post after we get a bit more info. Hang in there mines been back twice and I'm hoping not again
    Diag. 56 DOB 2/59 PSA Base 1.5 01/14 2.0 6/15 2.4
    Biopsy 6/15 5 Gleason Score 8
    RP 10/15 Path 54g 5x4.2x2.8cm 4+3=7 Tumor location quadrants Bilateral
    Extra-capsular extensions present,SV no invasion
    Vascular invasion none, PNI ,Multicentricity multifocal
    Margins No tPresent inked margins 5 neg pT3a,N0
    PSA 10/16 <0.1 02/7/17 1st BCR 0.4 02/15/17 0.5
    Pet Scan 2/17 Neg PSA 03/17 0.6 Axumin trial 17.4mm tumor rt. SVB Casodex + Trelstar
    04/17 SRT (42) to include location of tumor
    08/17 PSA 0.1 Last 6 uPSA 0.006 uPSA 2/19 0.030 2nd BCR 5/19 0.235 5/30 0.32 6/19 0.34
    7/19 0.06 8/19 0.08 9/19 0.05610/190 0.08 11/19 0.07 12/19 0.07
    7/19 Trelstar, Xtandi, Zoledronic Acid
    12/19 (3) SBRT Iliac bone liasion post SBRT 1/ 20 0.06 2/20 0.04 3/20 0.02 4/20 <.02 5/20 <0.02 6/20 <.02 7/20 <.014

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    Old 07-21-2020, 03:36 PM   #3
    xxsm's Avatar
    Join Date: Oct 2015
    Posts: 2
    xxsm HB User
    Re: Rising PSA

    Thank you Steve. The road got smooth after radiation. Now a few bumps... Aug 4th is the appointment. We'll see what happens.

    thank again

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    Old 07-22-2020, 05:35 AM   #4
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    Join Date: Nov 2007
    Location: Annandale, VA, USA
    Posts: 2,596
    IADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB User
    Re: Rising PSA

    Hi xxsm and welcome to the Board!

    An outstanding book with highly informative chapters on recurrence is "The Key to Prostate Cancer," 2018, by Dr. Mark Scholz, MD, and 29 others. It is designed so that you can focus only on the chapters that are most relevant (recurrence is mainly addressed in the chapters in the "Indigo" section), but with other chapters that you and your husband might also want to read. The medical oncology perspective on prostate cancer is well represented in the book, and it would help you prepare for the appointment. It is written in language that is easy to read for patients.

    Good luck!


    - - - - - - - - - - - - - - - - - - - - - - - -
    Diagnosis Dec 1999 PSA 113.6 (first ever), age 56
    Gleason 4+3=7 (J. Epstein, JHU), all cores +, most 100%; "rock hard" prostate with ECE - stage 3, PNI, PSADT determined later 3-4 months; technetium bone scan and CT scan negative; prognosis 5 years.
    Later ProstaScint scan negative except for one suspicious small area in an unlikely location. ADT Lupron as first therapy, in Dec 1999, then + Casodex in March 2000, then + Proscar and Fosamax in Sep 2000. Rejected for surgery January 2000; offered radiation but told success odds were low; switched to ADT only vice radiation in May 2000, betting on holding the fort for improved technology; PSA gradual decline to <0.01 May 2002. Commenced intermittent ADT3 (IADT3) with first vacation from Lupron & Casodex. Negative advanced scans in 2011 (NaF18 PET/CT for bone) and 2012 (Feraheme USPIO for nodes and soft tissue). With improved technology, tried TomoTherapy RT, 39 sessions, in early 2013, plus ADT 3 in support for 18 months (fourth round of IADT3), ended April 2014. Continuing with Avodart as anti-recurrence shield. Current PSA remarkably low and stable at <0.01; apparently cured. (Current T 99 6/5/20.) Supportive diet/nutrition, exercise, supportive medications during this journey, as well as switches in antiandrogen, 5-ARI, and bone drugs.

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    Old 07-22-2020, 06:18 AM   #5
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    Posts: 278
    Prostatefree HB UserProstatefree HB UserProstatefree HB UserProstatefree HB UserProstatefree HB User
    Re: Rising PSA

    Fyi, PSA testing after RP is not affected by physical activity such as sex or bicycle riding prior to the test.

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