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PCA3 Plus Test - Questions

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Old 08-09-2010, 12:32 PM   #1
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broderbund HB User
PCA3 Plus Test - Questions

I just returned from my urologist appointment. They took blood for another PSA and free PSA test and he did another DRE (everything felt fine) for a urine base PCA3 Plus test.

As I posted a few weeks ago, Iím 44 (PSA was a very stable 1.4 four months ago) but shot up to 4.9. Over the last month itís been bouncing up and down from 4.9 and now down to 3.6 after two weeks of Cipro. I also had my Free PSA taken last week on my own and it was 16.4 which it sounds like is a little on the low side (or at least not definitive enough to avoid a biopsy) ---- Iíve read where infection can also lower your free psa results.

My question is in regards to todayís PCA3 Plus test. My understanding is it can pick up prostate cancer cells in the urine and then the report comes back as a number (anything over 35 sounds as if PC is likely)
Couple questions I had about the test
1) What is the typical cut off number to avoid a biopsy?
2) How accurate is this test vs the free PSA
3) Why is this test not definitive ---- ie ---- if it picks up cancer cells it certainly seems that would translate to cancer being present. Guessing a lot of times the test comes back inconclusive leading to a biopsy?

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Old 08-09-2010, 09:23 PM   #2
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Re: PCA3 Plus Test - Questions

There are no markers that are 100% or 80% accurate.

When a marker(s) combined with family history indicate the possibility of PCa a biopsy is a helpful test to catch PCa early. If you have a biopsy find a center with a lot of PCa experience to maximize the chance of finding PCa if it is present. All options have a improved outcome with lower stages of PCa.

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