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PSA rising after Radiation Treatment

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Old 03-05-2012, 03:00 PM   #1
hulk1989's Avatar
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Location: Mitchell, South Dakota, USA
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PSA rising after Radiation Treatment

Hello all I have not posted for awhile as I finished my radiation treatment in early August. I have since had 4 PSA tests:
Mid September 6 weeks post treatment PSA=0.14
October 5th annual checkup PSA=0.13
December 9th PSA=0.19
Today March 5 PSA=0.42
The September and December tests were done by the same lab and the October and March tests were done by the same lab. I am wondering if anyone on this board has seen similar numbers. My biggest concern is that going by these numbers my doubling time is 3-4 months, is there a need for concern on my part, or is it possible that I am just seeing a bump like I have heard can happen post radiation treatment.

Although most of what I have read from others that have done radiation therapy that the PSA bump and nadir usually happen in the 12 - 24 month time frame, where mine seem to have both happened within the first 6 - 7 months post treatment. Any additional information anyone can supply will be greatly appreciated.


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Old 03-05-2012, 05:51 PM   #2
Tall Allen
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Re: PSA rising after Radiation Treatment

PSA bounces can and do happen anytime after radiation. Those are great numbers to have -- you should be thrilled rather than worried. It will be a couple of years before those numbers settle down. In fact, researchers have noticed correlations between the occurrence of bounces and lasting cures. The prevalent accepted (Phoenix) definition of "biochemical recurrence" is nadir+2, so if .13 turns out to be your PSA low point (nadir), nothing below a PSA of 2.13 is anything to worry about. Congratulations on your successful treatment.

- Allen

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