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Husband finished treatment

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Old 01-31-2013, 01:50 PM   #1
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Location: Idaho Falls, Idaho USA
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Question Husband finished treatment

Last spring my husband was diagnosed with PC. He had 4+3 gleason score and a PSA of >50. He was treated with 10 months of Lupron therapy (about six of those months he had the triple blockade). He also had brachytherapy last August. Then he had about 8 weeks of IMRT. He finished that in October. His Lupron should be wearing off as of January 1st. He was originally going to be on the hormone therapy for 12 months but he couldn't stand the side effects.

His most recent PSA was .08. Is this optimal or should it be even lower?

The other question is what is the chance that his testosterone won't come back up after the Lupron. I know it hasn't been very long but he is discouraged. He is still having hot flashes and "energy collapses" as well as being worried about memory issues and bowel issues. He says he is very tired of being sick.

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Old 02-01-2013, 09:49 PM   #2
Tall Allen
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Re: Husband finished treatment

I'm glad he got through treatment. The worst of that is over, thankfully.
I may have mentioned before that the best remedy for many of the deleterious effects of radiation and hormone therapy is exercise. Recent evidence shows it also boosts the immune response.

PSA of .08 sounds good to me, but expect it to go up as the Lupron wears off. There's a lot of irritated prostate tissue that will be releasing PSA into his bloodstream. It will slowly go down over time, and bounces are normal (in fact, they are associated with excellent outcomes). So while it's important to monitor PSA for several years, don't react too much to small or slow changes. Two years out and my PSA is still declining slowly, which is just fine with me.

Testosterone may stay low for a year or more. Everyone's different. Mine was low for about 18 months after RT, but then came back to very good levels. Again, exercise, especially weight-bearing, will be important while his T is low. If it doesn't come back eventually, it may be possible to take some measures to increase it. But for now, you don't want to do anything that might artificially interfere with his PSA.

- Allen

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prostate cancer, psa level prostate cancer, testosterone replacement

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