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Cancer: Stomach Message Board

  • Gallbladder and Diffuse Stomach Cancer

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    Old 01-17-2014, 12:17 PM   #1
    scattycat's Avatar
    Join Date: Jan 2014
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    scattycat HB User
    Gallbladder and Diffuse Stomach Cancer

    Looking at my 23 and me genetic information

    PSCA gene Marker rs2294008 Genotype TT means I have Substantially higher odds of diffuse-type stomach cancer.

    What sort of screening options are available to detect this?
    I have read that it is difficult to pick up on in Gastroscopy. I have GERD and Oesophagitis on Omeprazole.

    I have had my gallbladder removed and that showd dysplaysia (an unexpected finding) and have found a study where the PSCA gene variants (rs2294008 and rs2978974 confer increased susceptibility of gallbladder carcinoma in females. I am female and

    My genotype for these markers are
    rs2294008 (mine is TT)and for
    rs2978974 (mine is GG)

    So I thought I should maybe concerned about the diffuse stomach cancer risk

    My Paternal Grandfather died at 46. He had stomach cancer
    My Maternal Grandmother died being operated on for a stomach ulcer
    My mother died of breast cancer

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