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Melanosis coli anyone?

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Old 10-24-2013, 01:00 PM   #1
Join Date: Jun 2006
Location: Massachusetts
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melgag21 HB User
Melanosis coli anyone?

I was diagnosed with Crohns in June. The beginning of September had a very bad flare. Went to gi and they did. Colonoscopy the next day. It showed inflammation throughout colon, put on Asacol HD and Rowasa and scheduled to go back in 2 days. When I go back they also said I had c diff (they took a sample) so they sent me to the hospital. After a few days there, improving with liquids only and Vanco and flagyl for c diff they tell me the biopsies came back showing melanosis coli and I must be abusing laxatives. I was dumbfounded. The last laxatives I uses were the ones for the colonoscopy test. They wouldn't and still won't believe that I have not been a long term laxative abuser. I've had 3 EGDs all showing inflammation. I need a laxative like I need a hole in my head! So they discharged me with a diagnosis of "suspected laxative abuse". Without me knowing they did a laxative screen there and then when I followed up with gi dr and both were negative. I am so hurt that the drs so not believe me. I have found a few places that say melanosis coli can be attributed to increases cell apoptosis and that can be def related to IBD. So my question- anyone else with an IBD have a biopsy show melanosis coli or been accused of abusing laxatives and what did you do? I don't know what to do since both my laxative screens came back negative. This has consumed me since then and I'm so sick and anxious over it.


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Old 10-29-2013, 06:24 PM   #2
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Re: Melanosis coli anyone?


I had never heard of Melanosis Coli. I looked it up, merely a change in pigmentation and a few other features. It did mention laxatives as a cause. As you imply, most people with UC or Crohn's can't even look at laxatives on a store shelf without feeling sick. Sometimes Crohn's patients get partial or full small bowel obstructions and a very few of them will turn to laxatives with disastrous results.

It would be entirely okay to admit such a thing, wouldn't it? Not to imply that you have done this... but, have you felt constipated at all in the past? Have you ever had a bowel obstruction?

You could share with them how their incorrect conclusions have upset you greatly and demand some sort of apology. You can also get a new set of Doctors. Try to let it go if you can. Go back in a few months and get yourself retested, if the condition persists then they need to figure it out, right?


Last edited by Isotope; 10-29-2013 at 06:30 PM.

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