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-   -   L-Tyrosine and DL-Phenylalanine for depression (https://www.healthboards.com/boards/depression/255067-l-tyrosine-dl-phenylalanine-depression.html)

ftlmatt 02-20-2005 07:58 PM

L-Tyrosine and DL-Phenylalanine for depression
 
which one of these amino acids, taken on an empty stomach, is more helpfull in improving mood.
i know l-tyrosine is the precursor to dopamine..but i already take dexedrine for add and wellbutrin for depression, both working on dopamine..
and that l-phenylalanine is the precursor for norepinephrine..
has anyone had any experience with these and which one works better than the other? any responses would be greatly appreciated

EoR 02-20-2005 08:04 PM

Re: L-Tyrosine and DL-Phenylalanine for depression
 
[QUOTE=ftlmatt]which one of these amino acids, taken on an empty stomach, is more helpfull in improving mood.
i know l-tyrosine is the precursor to dopamine..but i already take dexedrine for add and wellbutrin for depression, both working on dopamine..
and that l-phenylalanine is the precursor for norepinephrine..
has anyone had any experience with these and which one works better than the other? any responses would be greatly appreciated[/QUOTE]

I'm not sure about either, but I have heard that it can be dangerous to take natural drugs alongside prescribed ones. You might want to run it by your doc before trying it.

:) <-EoR->

rose_5-HT 02-20-2005 08:49 PM

Re: L-Tyrosine and DL-Phenylalanine for depression
 
[QUOTE=ftlmatt]which one of these amino acids, taken on an empty stomach, is more helpfull in improving mood.
i know l-tyrosine is the precursor to dopamine..but i already take dexedrine for add and wellbutrin for depression, both working on dopamine..
and that l-phenylalanine is the precursor for norepinephrine..
has anyone had any experience with these and which one works better than the other? any responses would be greatly appreciated[/QUOTE]

For me the main problem is that both l-tyrosine and l-phenylalanine are neutral aminoacids and they will compete with l-tryptophan for entry thru the blood brain barrier. This will mean lower synthesis of serotonin => increased depression.

I made the experiment several times with large single dose of different neutral aminoacids and each time I get acutely depressed and suicidal within hours (no fun at all to live). Even taking l-tryptophan afterwards hardly brings any relief. Only time (1 week - 10 days) allows total recovery :)

Rose_5-HT

glo81 02-20-2005 08:59 PM

Re: L-Tyrosine and DL-Phenylalanine for depression
 
I take 50mgs of 5htp w/10mgs of vit. b-6 and 750mgs of Gaba at night. In the morning I take 500mgs of L-tyrosine. Seems to work well for me right now. Any other opinions welcome.

ftlmatt 02-21-2005 10:00 AM

Re: L-Tyrosine and DL-Phenylalanine for depression
 
[QUOTE=EoR]I'm not sure about either, but I have heard that it can be dangerous to take natural drugs alongside prescribed ones. You might want to run it by your doc before trying it.

:) <-EoR->[/QUOTE]

actually those aren't natural drugs...they are amino acids that are just two of the many that make up protein..
and i know more about medications and diet than most my doctors lol

ftlmatt 02-21-2005 10:04 AM

Re: L-Tyrosine and DL-Phenylalanine for depression
 
[QUOTE=rose_5-HT]For me the main problem is that both l-tyrosine and l-phenylalanine are neutral aminoacids and they will compete with l-tryptophan for entry thru the blood brain barrier. This will mean lower synthesis of serotonin => increased depression.

I made the experiment several times with large single dose of different neutral aminoacids and each time I get acutely depressed and suicidal within hours (no fun at all to live). Even taking l-tryptophan afterwards hardly brings any relief. Only time (1 week - 10 days) allows total recovery :)

Rose_5-HT[/QUOTE]

actually l-typtophan molecules are larger than tyrosine and phenylalanine so it is harder to absorb....but the best way to take amino acids, if u take them individually, is on an empty stomach.
i am not a big fan of precursors to serotonin since my depression and ADD are most likely due to dopamine and norepinephrine...i know this because none of the ssri's worked for me

EoR 02-21-2005 10:25 AM

Re: L-Tyrosine and DL-Phenylalanine for depression
 
[QUOTE=ftlmatt]actually those aren't natural drugs...they are amino acids that are just two of the many that make up protein..
and i know more about medications and diet than most my doctors lol[/QUOTE]


Shrug. I guess I call anything that can be taken to alter mood/mind/body, etc. that isn't prescribed by a doc a "natural drug." :) I guess my "best advice" at this point would be to try them both and decide for yourself :) But then again, nobody solicited my best advice. Lol. Good luck to you. :jester:

-EoR-

kiehn 02-21-2005 10:35 AM

Re: L-Tyrosine and DL-Phenylalanine for depression
 
I also take DL-DL-Phenylalanine 1000mg, L-Tyrosine 1000mg, Gaba 750mg, L-taurine 1000mg, B-6 500mg, Choline (Bipolar) 1600mg my depression and swings are 3 times
as bad. K I had RLS for over 3 years and by accident found the DL-phenylalanie
which is sometimes used for Parkinson's helped my RLS. K


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