L-Tyrosine and DL-Phenylalanine for depression
 

which one of these amino acids, taken on an empty stomach, is more helpfull in improving mood.
i know l-tyrosine is the precursor to dopamine..but i already take dexedrine for add and wellbutrin for depression, both working on dopamine..
and that l-phenylalanine is the precursor for norepinephrine..
has anyone had any experience with these and which one works better than the other? any responses would be greatly appreciated

Re: L-Tyrosine and DL-Phenylalanine for depression
 

[QUOTE=ftlmatt]which one of these amino acids, taken on an empty stomach, is more helpfull in improving mood.
i know l-tyrosine is the precursor to dopamine..but i already take dexedrine for add and wellbutrin for depression, both working on dopamine..
and that l-phenylalanine is the precursor for norepinephrine..
has anyone had any experience with these and which one works better than the other? any responses would be greatly appreciated[/QUOTE]

I'm not sure about either, but I have heard that it can be dangerous to take natural drugs alongside prescribed ones. You might want to run it by your doc before trying it.

:) <-EoR->

Re: L-Tyrosine and DL-Phenylalanine for depression
 

[QUOTE=ftlmatt]which one of these amino acids, taken on an empty stomach, is more helpfull in improving mood.
i know l-tyrosine is the precursor to dopamine..but i already take dexedrine for add and wellbutrin for depression, both working on dopamine..
and that l-phenylalanine is the precursor for norepinephrine..
has anyone had any experience with these and which one works better than the other? any responses would be greatly appreciated[/QUOTE]

For me the main problem is that both l-tyrosine and l-phenylalanine are neutral aminoacids and they will compete with l-tryptophan for entry thru the blood brain barrier. This will mean lower synthesis of serotonin => increased depression.

I made the experiment several times with large single dose of different neutral aminoacids and each time I get acutely depressed and suicidal within hours (no fun at all to live). Even taking l-tryptophan afterwards hardly brings any relief. Only time (1 week - 10 days) allows total recovery :)

Rose_5-HT

Re: L-Tyrosine and DL-Phenylalanine for depression
 

I take 50mgs of 5htp w/10mgs of vit. b-6 and 750mgs of Gaba at night. In the morning I take 500mgs of L-tyrosine. Seems to work well for me right now. Any other opinions welcome.

Re: L-Tyrosine and DL-Phenylalanine for depression
 

[QUOTE=EoR]I'm not sure about either, but I have heard that it can be dangerous to take natural drugs alongside prescribed ones. You might want to run it by your doc before trying it.

:) <-EoR->[/QUOTE]

actually those aren't natural drugs...they are amino acids that are just two of the many that make up protein..
and i know more about medications and diet than most my doctors lol

Re: L-Tyrosine and DL-Phenylalanine for depression
 

[QUOTE=rose_5-HT]For me the main problem is that both l-tyrosine and l-phenylalanine are neutral aminoacids and they will compete with l-tryptophan for entry thru the blood brain barrier. This will mean lower synthesis of serotonin => increased depression.

I made the experiment several times with large single dose of different neutral aminoacids and each time I get acutely depressed and suicidal within hours (no fun at all to live). Even taking l-tryptophan afterwards hardly brings any relief. Only time (1 week - 10 days) allows total recovery :)

Rose_5-HT[/QUOTE]

actually l-typtophan molecules are larger than tyrosine and phenylalanine so it is harder to absorb....but the best way to take amino acids, if u take them individually, is on an empty stomach.
i am not a big fan of precursors to serotonin since my depression and ADD are most likely due to dopamine and norepinephrine...i know this because none of the ssri's worked for me

Re: L-Tyrosine and DL-Phenylalanine for depression
 

[QUOTE=ftlmatt]actually those aren't natural drugs...they are amino acids that are just two of the many that make up protein..
and i know more about medications and diet than most my doctors lol[/QUOTE]


Shrug. I guess I call anything that can be taken to alter mood/mind/body, etc. that isn't prescribed by a doc a "natural drug." :) I guess my "best advice" at this point would be to try them both and decide for yourself :) But then again, nobody solicited my best advice. Lol. Good luck to you. :jester:

-EoR-

Re: L-Tyrosine and DL-Phenylalanine for depression
 

I also take DL-DL-Phenylalanine 1000mg, L-Tyrosine 1000mg, Gaba 750mg, L-taurine 1000mg, B-6 500mg, Choline (Bipolar) 1600mg my depression and swings are 3 times
as bad. K I had RLS for over 3 years and by accident found the DL-phenylalanie
which is sometimes used for Parkinson's helped my RLS. K