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"Leaden Paralysis?"

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Old 01-02-2006, 12:32 PM   #1
Join Date: May 2005
Posts: 368
OraEtLabora HB User
"Leaden Paralysis?"

This is my first time posting on this board, so I hope someone can help me. I usually post on the thyroid board.

For 16 years I've been disabled due to what I have just found out is called "leaden paralysis." During that time, I also had autoimmune thyroid disease that was completely missed - until 2 years ago, because my TSH was always "normal." So, I was very ill, with a lot of symptoms, and each year became sicker and sicker. But the worst symptom was this "leaden paralysis" - I just found out what it was called a few days ago, when I did an internet search. It feels like I have a ton of lead in all my muscles. They hurt horribly, and to move involves enormous effort. In fact, it takes hours of mental "psyching up" just to get myself up out of bed - forget getting dressed! Yesterday, I sat in a chair for 12 hours, because I was too exhausted to get up.

During the 16 years, I have tried just about every anti-depressant made, but none helped, at all. However, now that I am being treated for my thyroid, I have found some relief, almost immediately, with Effexor XR. In fact, the first day I took the Effexor, I felt the "lead" lift, and I could get my house cleaned and some other activities done that I was unable to do before. It was as if someone lifted a giant leaden blanket off of me, and I could move with such ease! I felt like turning cartwheels!

But, the effect wore off after a couple of weeks, and the side effects (very loud ear ringing, "brain shakes" and severe constipation) were so horrible that I had to discontinue by tapering off over a period of several weeks. Now, I am seriously depressed because I have had some relief for the first time in 16 years, only to lose it, and to find myself back to where I was. It would have been better if I had never had a "taste of wellness," because it makes it harder to go back to the hell I have lived for 16 years.

This "leaden paralysis" is associated with "atypical depression," which I am sure I have since I am usually very happy, and never feel sad or depressed. My question is, has anyone else experienced this "leaden paralysis," and have you felt any relief from it? I am thinking of trying "Cymbalta" but don't know if it will be any better than the Effexor XR.

Bless you for any help you can offer.


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