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What is the real problem of taking MAOI & Nyquil?

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Old 04-14-2007, 07:57 AM   #1
Join Date: Apr 2007
Location: CA
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Zoom33 HB User
What is the real problem of taking MAOI & Nyquil?

I see the warning on the Nyquil bottle now…. I never liked taking any kind of medication to begin with, but sometimes you just have to. I’ve started taking Lexapro about 3 month ago because of my depression symptoms. Gradually increased my caffeine (just coffee) intake from once in 2 weeks to twice a day! Lexapro just makes me sooooo groggy. I remember doctor asking me how much caffeine I intake when prescribed the Lexapro, so I assume there is some kind of relationship between two.
I actually hate the thought that I am offsetting the side effects of the medication with stimulant that normally is probably worsens the symptoms for which I am taking the medication. Enough overtures I stopped Lexapro about a week ago & did not experience any withdrawal effects, but I got a pretty bad cold and had taken Nyquil for 3 days. After “side effects” of practically taking both at the same time (as I understand this stuff stays in your body for at least 2 weeks) I did read the warning label on the Nyquil and noticed no MAOIs & Lexapro is not an MAOI right? So what is the deal of those two interacting? I am just tying to figure out if my “side effects” are result of stopping the Lexapro or mixing the meds. Thanks for looking/answering/suggesting.

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Old 04-14-2007, 11:00 AM   #2
Join Date: Apr 2007
Location: Florida
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luckygem13 HB User
Re: What is the real problem of taking MAOI & Nyquil?

Lexapro is an SSRI, it is very safe. It didn't make me groggy at all but I had a rare side of effect of bruising and a little trouble sleeping. The MAOI's don't mix well with a lot of things, the problem with mixing things with the MAOI's I believe is a risk of a spike in blood pressure causing a stroke or even death.

Old 04-14-2007, 04:27 PM   #3
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Kiasmama HB User
Re: What is the real problem of taking MAOI & Nyquil?

MAOIs just work in a different way. They deal with blocking the MAO enzyme rather than just opening or closing receptors which is basically what the SSRIs do. When you deal with enzymes you have a greater capacity to affect other areas of the body. There are food interactions to worry about that can cause a release of a neurotransmitter norepinephrine...which can cause some severe physical reactions. When someone is on MAOIs they need to watch their diet closely....they are usually prescribed when the SSRIs dont' work.

Old 04-14-2007, 04:55 PM   #4
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Seymour93 HB User
Re: What is the real problem of taking MAOI & Nyquil?

luckygem13 is right about maoi's. The spike in blood pressure is the danger... No need to worry. Good luck.

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