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Anyone tried Valtrex for Chronic EBV?

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Old 08-23-2009, 04:16 PM   #1
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Anyone tried Valtrex for Chronic EBV?


I've had chronic epstein barr virus infection for the past 16 months. I first started taking acyclovir in 12-08 for 6 months but didn't notice significant improvement. I'm not bedridden but I have to sleep 10-12 hours a day and still wake up tired.

I then changed to taking Valtrex 6 weeks ago (500 mg 3 times a day & I weigh 105 lbs). Weeks 1-2, I wasn't noticing difference. Weeks 3-4, I was feeling a lot worse; I'm not sure if maybe the Valtrex was working or if I just over-exhausted myself (I had a very long day before things got worse). Week 5, I felt like maybe there were some signs of recovery. I've been getting lots of rest, and Week 6 - I feel like I'm back to where I was before the Valtrex and wonder if it is even working.

-- Is or was anyone on Valtrex for treatment of chronic EBV or chronic fatigue in general?
-- If so, how long did it take to see improvements? Did it get worse before it gets better?

I'm just puzzled because I don't know if the Valtrex is working for me. I'm supposed to take it for 6 months for the treatment, but I'm supposed to start working again in 3-09, and I just don't have endless 6-months to keep trying new drugs and end up finding out that they don't work.

Thank you in advance for your help!!

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Old 08-26-2009, 04:38 PM   #2
the tortoise
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Re: Anyone tried Valtrex for Chronic EBV?

From what Iíve read, Valtrex will work if the ONLY viral infection is EBV. Two other viral co-infections frequently found with EBV are HHV-6 and CMV. You should be tested for co-infections starting with those two. If you have either in addition to the EBV some people have found Valcyte to be useful.
Good luck, tt

Old 08-27-2009, 11:12 AM   #3
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Re: Anyone tried Valtrex for Chronic EBV?

Thanks, tt. I have been tested for HHV-6 and CMV and some other viruses/bacteria. No CMV and HHV-6 is very low that it shouldn't be the cause of fatigue.

I'm trying to find out if Valtrex works for everyone who only has an EBV infection, or only a subset. Please let me know if you happen to know; thanks.

Old 08-28-2009, 07:25 AM   #4
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Re: Anyone tried Valtrex for Chronic EBV?

It IS working for me. I sent you a message did you get it?

I read the doctor you are seeing had studies going in 2007 at Stanford. And he got a good response to antivirals.

It just takes time. Cause like with everything it depends on each individual's body.

Took at least 8months of Valtrex before I started seeing any improvement.

Keep at it.


Old 08-28-2009, 09:17 PM   #5
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Re: Anyone tried Valtrex for Chronic EBV?

Hi Jodie,

Thanks for this message. For some reason, your earlier message didn't get through the email filter; I'm so glad that I was able to retrieve it!

Thanks very much for your response! I will try to be patient and also work on having a better sleep schedule too and see if it helps.

Take care,


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