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Adie's Tonic Pupil - Pilocarpine Drops?

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Old 05-09-2006, 09:31 AM   #1
Join Date: May 2006
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HorsieLuver HB User
Adie's Tonic Pupil - Pilocarpine Drops?

Hey all,

My fifteen yr old daughter's left pupil has been dilated for 8 months. We had a CT scan, which requested we do an MRI. The MRI was unable to get pics as she wears braces, and it effected the show of her brain. The braces are coming off tomorrow, and we are waiting for a call on a new MRI.

After waiting 4 months, we finally got in to see an opthalmalogist, who thinks it could be Adie's Tonic Pupil. He has only see 3 cases of a person with a blown pupil - one from a stroke, one from a ceberal 3rd nerve palsy, and one from Adie's. So he decided to do the pilocarpine drop test. Her eye should have been EXTREMELY sensitive to the drops...but they didn't react at all. She has been putting them in 4x a day, for 3 days, and we see him Thursday.

Has a blown pupil effected anyone else here? Please help us out! Thanks

Last edited by HorsieLuver; 05-09-2006 at 10:03 AM.

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Old 05-09-2006, 02:25 PM   #2
Join Date: May 2006
Posts: 6
HorsieLuver HB User
Re: Adie's Tonic Pupil - Pilocarpine Drops?

does anyone know?? help us out, please!!

Old 05-09-2006, 07:24 PM   #3
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Join Date: Jun 2005
Location: Naples,FL
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twoeyez HB Usertwoeyez HB User
Re: Adie's Tonic Pupil - Pilocarpine Drops?

Adie's pupil is a neurological condition of unknown origin with an unusual, asymmetric presentation known as anisocoria, an inequality in the size of the pupils of the eyes. It is believed to be a result of damage to the nerve innervating a muscle of the eye known as the ciliary body. Alternately, the problem may be located at the ciliary ganglion, a kind of nerve junction structure from which the nerve to the ciliary body runs. Accommodation, or the adjustment of the eye for distance, is affected, as well as pupillary dilation and contraction, the ability of the eye's iris to open or close in response to ambient light. Adie's pupil primarily affects women from 20 to 40 years of age. It is considered to be a benign condition with no known cure. When Deep Tendon Reflexes (DTRs) of the legs—knee and ankle jerks—are also affected, accompanied by symptoms including localized, discreet areas of the skin that do not sweat, postural hypotension (low blood pressure related to sudden standing or rising), and unsteady heart rhythms, the condition is referred to as Adie's syndrome.

If pilocarpine drop test did not cause the pupil to constrict,then there is some other nerve innervating problem. Question the heavy dose of pilocarpine 4x/day for 3 days.
Keep in touch with what the Eye Dr. has to say on thursday.


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