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    Old 07-06-2006, 01:10 AM   #1
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    Anyone know anything about Cymbalta?

    Hey! I'm new to the boards and would appreciate any info offered.

    A year ago I was diagnosed with CFS and four months after that fibro. Also, just recently diagnosed with IBS. Its been an uphill battle the whole way. I've traveled out of state to see a specialist who has prescribed Cymbalta and Triavil. I haven't heard great things about Cymbalta and no on seems to have even heard of Triavil. I haven't started the meds yet because I'm a bit nervous.

    Has anyone used these? Any positive results or horror stories?

    Thanks in advance for the replies!


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    Old 07-06-2006, 09:36 AM   #2
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    I will tell you GEAT things about CYMBALTA... I have been on it for about a yr and a half.. it has reduced my pain level by at least half!!!! it doesnt do a whole lot for my major depressive disorder... but, for the fibro it is wonderful!! I also have ibs and cfs and a bunch of other acronyms.. lol I am currently taking 60 mgs of it.. i take mine at night but only since it doesnt energize me and I take my other depression meds at night to help me sleep.. ( which they dont help either but i need them for the depression) I use ambien to sleep every single evening!

    For pain I use darvocett N 100, it has been the most helpful... I was on methadone but quit taking it.. They were afaid my liver functions were elevated by the tylenol in the darvocett, but it wasnt that! so i went back to the darvocett.

    Old 07-06-2006, 10:17 AM   #3
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    Re: Anyone know anything about Cymbalta?

    Hi Greg,

    Studies I have read indicate that while antidepressants are widely prescribed for fibro, only about 25% of those with fibro experience significant pain reduction from that particular treatment protocol. However, if you happen to be one of the 25 %, you may hit the jackpot. I notice that, while IndySasha finds Cymbalta helpful, she still takes narcotic medication.

    SSNRIs like Cymbalta are currently being heavily promoted by Pharma. No doubt you have seen the "depression hurts" ads on TV. This ad really irritates me, as it fails to recognize the more common scenario, that chronic pain leads to brain changes & depression. Perhaps a fine distinction, but it's not helpful to reverse cause & effect. It does give me pause when a doc upfront recommends the hot drug.

    Fibro (in past known as "fibrositis") has a reputation as a women's disease & carries some stigma as a result. For a LONG time, all that was promoted medically were AD drugs like amitryptilline (related to Triavil), because it was believed all fibro sufferers were just somewhat depressed, or somatizing. In a nutshell that all fibro was a psychiatric problem, "hysteria," in the Freudian sense. Since that time, there has been a little progress in med research, showing that our pain is "real."

    There is no doubt that for many folks the SSNRIs like Cymbalta & Effexor are energizing. And that can help fatigue. However, side effects are not uncommon from these meds. And in particular, weaning off the SSNRIs can be a nasty (though not impossible) experience. In some cases, the SSNRIs are helpful for a period of time, then lose their effectiveness for fibro issues. But, of course, if one has a good year, 2 yrs., whatever, that is not to be dismissed.

    I am surprised that your doc has Rxd the Cymbalta & Triavil together. Perhaps you suffer from a longstanding major depressive disorder? If so, that may be appropriate. I would hope that you have thoroughly researched these drugs & are comfortable with their potential side effects. It's fairly simple to pop a drug name into a search engine & find oodles of info.

    Since fibro is a diagnosis arrived at by eliminating other possible causes for symptoms, I would hope that you have had an extremely thorough physical workup. All too frequently endocrine problems are an overlooked contributing factor to the symptoms of fibro. Thorough assessment of thyroid function (beyond a TSH screen), adrenal function, and testosterone level will often pick up subtle abnormalities which, when addressed, can make a world of difference.

    I am not attempting to bash the meds you have been Rxd. I wish you well, but hope you will be cautious in your approach to medical recommendations. Let us know if the meds help.

    Best wishes.

    Old 07-06-2006, 11:01 PM   #4
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    Re: Anyone know anything about Cymbalta?

    I have been on Cymbalta twice. Once almost two years ago for 7 mos and it worked very well...but after awhile stopped helping. I gave it another try in September 2005 and still taking. It makes a great difference with the pain, even though I do need to take Ultram at times, such as rainy weather (bad pain no matter what you take, but Ultram takes the edge off.) I did recently try to get off and within a few days the pain was terrible. When I got back on the pain levels decreased very much. I have not personally had any bad side effects and have done extensive research on the drug. (Of course there are no guarantees on any drugs.

    Just my experience...

    Old 07-07-2006, 01:19 PM   #5
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    Re: Anyone know anything about Cymbalta?

    Hi Greg. I was prescribed cymbalta 6 wks ago, 30 mg at bedtime, getting ready to raise it to 60 mg. I honestly haven't noticed any changes other than I am sleeping a little better, but thats probably from the muscle relaxers.I'll keep on it for a while and see if theres any improvement. I also take Fiorcet, and Zanaflex. Zanaflex is what helps me sleep.

    Old 07-08-2006, 03:16 AM   #6
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    Re: Anyone know anything about Cymbalta?

    My Husband Was Prescribed Cymbalta For Nerve Pain. Had Now Problem With It Except Having A Hard Time Sleeping At Firs. Cut His Appetite So He Lost Some Weight. Really Helped With The Pain.

    Old 07-08-2006, 11:21 PM   #7
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    Cool Re: Anyone know anything about Cymbalta?

    Hi. Greg I have been taking Cymbalta for about 2 months now. I was previously taking Effexor so had to slowly go off that as I was going up with the Cymbalta. I am currently take 60 mg. In this past week I have noticed that I have been feeling better. I still take trammadel and Vicoprofen for pain but my mood is improved and I have a bit more energy which coming from zero is better than none! As for the triavil, my mom took it starting in 1966 and it worked wonderful for her depression. When she tried to go off and try something else, she always went back to it. This was for a major depression, not for any pain. I know it is one of the older anti-depressents out there. I was told it had a combination of elavil and something else? I haven't heard of anyone trying it for Fibro. I have tried all of them (I think) elavil, paxil, prozac, effexor and now the Cymbalta. But-When you are sufferering you will try just about anything. I was told by the Pain Doc i just started seeing that Cymbalta and Lyrica are the two newest ones that seem to help people with this type of pain. I agree with elmhar to research to find out all the info you can, but I also agree that the big drug companies really push for you to use their stuff. After 20 + years of this Fibro/Chronic Pain, I wish I had more answers for myself so I could pass them on, but this is one mysterious monster to handle. Good Luck and remember Drs. are not always as informed as the patients. You have to guide them along and tell them what you want to try. Good Luck and keep your chin up Lefty

    Old 07-10-2006, 02:36 PM   #8
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    Re: Anyone know anything about Cymbalta?

    I have been on 30mg of Cymbalta for over 2 yrs. and I find that I'm happier than I have ever been even with the good ol' Fibro pain. I also take 1mg. of Clonazepam which helps me sleep and is a mild muscle relaxer. I can't really say whether or not cymbalta helps with the pain. Hope all these replies helps you make a decision.

    Good Luck and Good Heath

    Old 07-10-2006, 02:52 PM   #9
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    Re: Anyone know anything about Cymbalta?

    I have been on Cymbalta for over a year, with no side affects. I also get plenty of excersice, and I currently am off all other pain meds, and muscle relaxers. It works great for me, but I know others whom can't take it. With Fibro I sometimes think it's a hit or miss with the RX's we take. ( I have had more misses) Thanks to Cymbalta I feel great!!!! Hope you find the magic mixture that works for you!

    Old 08-07-2006, 10:13 PM   #10
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    Re: Anyone know anything about Cymbalta?

    I haven't been diagnosed with fibro, but when I started having leg pain a few years ago, my psychiatrist prescribed Cymbalta (I have bipolar disorder). I did notice it helped the pain (and the depression a bit too). I quit taking meds though, because I felt like my doc was prescribing too i wish i was still on cymbalta...

    Old 08-09-2006, 04:39 PM   #11
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    Re: Anyone know anything about Cymbalta?

    Our daughters have tried Cymbalta. One can not keep it down at all. It is out of her system in an hour and then lays on the couch for a day after. She has tried it twice. The other got more and more "I don't care" the longer she took it and as they increased the dosage. It didn't help. The daughters must not be of that 25% that antidepressants help. We still haven't found something that actually relieves the symptoms.

    Old 08-15-2006, 10:37 AM   #12
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    Re: Anyone know anything about Cymbalta?

    I have been on Cymbalta for three weeks, and so far, I hate it. I feel jittery, tense, irrational and anxious much of the time and I am having a hard time sleeping. Most days I feel like I slept 3 hours and then drank nine cups of coffee. Awful dry mouth too... So far, it's done nothing for the pain either.

    Does it get better? I know that some SSRIs take several weeks to "kick in" and the side effects tend to be the worst the first few weeks. I don't know enough about Cymbalta to know if it works the same way.


    Old 08-15-2006, 01:51 PM   #13
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    Re: Anyone know anything about Cymbalta?

    Mary -

    It took a good 5-6 weeks before I really started feeling the effects of Cymbalta. Hang in there, because you'll notice a big difference then in your mood and possibly you pain level as well.


    Old 08-22-2006, 09:29 PM   #14
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    Re: Anyone know anything about Cymbalta?

    The only thing that bothered me about Cymbalta was the nausea. It went away after awhile, though. Sometimes though, I would forget me medication for a few days, and when I finally remembered to take it, the nausea came back...

    Old 08-29-2006, 02:48 PM   #15
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    Re: Anyone know anything about Cymbalta?

    I have been in a study since last October using cymbalta for fibro. I have no idea what dosage I had in the first part of the study but in the last half I have been taking 120 mg of the Cymbalta every morning.

    I knew the first day I was not on placebo because my appetite was cut. (I have lost over 20 lbs in the study.) It took two week for the meds to kick in. I have gone from crying out when he touched each of the 18 tender points on the first check up to him using a tool to measure how much pressure he is applying to the tender points and saying "It hurts there". I have been thinking creatively again, exercising, and participating in life a lot more. It has been wonderful for me. I am not depressed, nor have I ever been. I do however have chemical sensitivity and the Cymbalta does nothing for that.

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