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  • Which tests to discover reasons for unexplained weight loss

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    Old 01-19-2016, 07:19 AM   #1
    window1
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    Which tests to discover reasons for unexplained weight loss

    My background
    I have unexplained weight loss from 83kg to 74kg in six month for 5.6’. I carry on losing weight about 1 kg every two weeks. I am very worried because I went to my GP already six weeks ago and if I have a serious disease it could have spread a lot in six weeks.

    I am 51 years old. I have a sedentary lifestyle because I am sitting a lot. I used to eat t a lot of processed foods but I stopped seven years ago and I replace it by fruits

    I am a former smoker who smoked for eight years and I quitted twenty years ago and as a consequence I become overweight. Hence I am an history of being overweight. I am worried because cancer is more common with overweight people specially colon cancer which is one of the more common type of cancers

    My symptoms
    I am tired from time to time specially after eating
    Sometimes the morning I need to go quickly to toilet otherwise I lose my stools
    Sometimes I lose a little stools and I have itching in my bottom
    When I eat a lot I have a pain in my belly
    Sometime my heart vibrate and I have a discomfort
    I need to urinate often and sometimes urgently especially when I walk with a big pain in my belly and discomfort in my left side. I have this symptom for the last 18 years but it has become worse

    The tests I have done
    I have done an endoscopy, an abdominal CT scan and a blood test all were ok but I do not know if all these tests are entirely sure and maybe I need further tests to confirm them
    The endoscopy shows a gastritis but I have no diarrhoea or constipation and I have heard that my gastritis could not be the reason for my unexplained weigh loss

    How to find the reason of my weight loss?
    I have heard that weight loss is a late symptom of cancer but I have heard also that in the vast majority of cases of cancer, other symptoms will develop before any weight loss. However, occasionally also, weight loss is the first symptom noticed and it is what worries me

    There are a lot of references to early stage and advanced stage of cancer but there could be also an intermediate stage during which some first symptoms appear like weight loss but nothing appears yet in the blood test
    The question is why I am losing weight? I would like to know which other tests I need to do to finally discover the reason. I am thinking to the following tests:

    Stool test
    I heard that a stool test is a must because I can have a worm or blood in my stools

    A rectal examination

    A colonoscopy
    Maybe a colonoscopy could be good to rule out any other bowel diseases?
    I heard that a colonoscopy should be made for the over 50 every ten years
    I can do only a stool test but a colonoscopy will find also colorectal polyps
    A colonoscopy could be good for the sake of completeness because the colon is one of the parts of my body which was has not yet been checked by the other tests that I have done

    An ERCP
    To be sure that I have nothing wrong with my liver and my pancreas. I am worry because I heard that liver can work without pain even if only a part of it works

    An X ray or a chest CT scan
    I know that in other European countries an X-ray of the chest is done during regular check-ups. Moreover I am a former smoker and have heard that weight loss could be a sign of lung cancer. The chest is one of the parts of my body which have not yet been checked by any of the other tests that I have done

    Screening of my urine
    I have not yet done any urine test. I am thinking to urinalysis, urine cytology, and urine tests for tumour markers. It could good I have several urine tests because I have heard that there could be blood in urine one day but not another day

    I need also to investigate my frequent and urgent need for urinating so maybe a CT urogram is necessary. Moreover the abdominal CT scan that I have done does not always show bladder cancer

    Maybe I have an endocrine disorders and I would like to know which other tests I need to do to find the reason

    Maybe I have only an infection but how to be sure and in case I have an infection how to find it. Moreover I have no diarrhoea or constipation which could be the sign of infection. So maybe other texts could be necessary to discover an infection and I would like to know which

     
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    Old 01-19-2016, 08:11 AM   #2
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    Re: Which tests to discover reasons for unexplained weight loss

    You have listed some helpful tests, some of which are more important than others. Cancer should definitely be ruled out, as well as diabetes (causes weight loss and frequent urination) and thyroid over-activity. These are blood tests. You should have a chest xray to start, follow up chest CT if anything abnormal shows on xray. You should have stool tests for hidden blood. Blood tests for liver and pancreatic enzymes. Urine check for infection/blood/protein/bilirubin. A colonoscopy is a must if nothing shows up on these other things. That can be scheduled and the other tests done while waiting for colonscopy to be done. This amount of weight loss is serious and must be investigated ASAP. Hopefully, it is something hormonal that can be treated or if it is cancer, picked up early enough to cure. Let us know what you find out.

     
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    Old 01-19-2016, 10:57 AM   #3
    window1
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    Re: Which tests to discover reasons for unexplained weight loss

    I have done a blood test during a check up in November in my GP practice and another in January in the hospital after I was referred for my unexplained weight loss. I suppose that these two blood tests cover all information to which you make reference in your reply about blood tests. During the last blood test five samples of my blood were taken. I do not know if it is what we called a ‘Comprehensive Metabolic Panel’. What is strange is that for the first blood test in November I was told not to eat anything the morning but for the second blood test in January I was told that it was irrelevant whether or not I eat the morning but I nevertheless ate nothing in case what was told to me was wrong. I do not know if this means that these two blood test were different

    Both tests were Ok. So if I have properly understood what remain to be done is a urine test, a stool test, a chest xray and a colonoscopy

    On Thursday I have an appointment with my consultant and I will ask him to do these tests hoping he will agree

     
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    Old 01-19-2016, 01:51 PM   #4
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    Re: Which tests to discover reasons for unexplained weight loss

    Your weight loss, fast bowels, and heart "vibration" (and other kinds of palpitations) would be classic signs of hyperthyroidism, so you need a thyroid workup. At a minimum, you need blood tests for TSH, free T4, free T3, and TSI antibodies.
    The belly pain isn't a common sign of thyroid disease, however.
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    Old 01-19-2016, 02:56 PM   #5
    window1
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    Re: Which tests to discover reasons for unexplained weight loss

    I do not know which blood tests I have made so I will ask to the consultant when I will see him next Thursday. I am not sure that I did a PAS blood test for prostate cancer during my first blood test in November in my GP practice for my check up. However maybe I did it during my second blood test in the hospital in January because the nurse took five samples of my blood. I asked to the nurse why she took five samples of my blood she replied that it was one for each possible problems and I remember she made reference to the thyroid but I do not remember if she made mention to the prostate. The question is would have the consultant asked also for a PAS blood test for prostate cancer knowing that I have unexplained weight loss?

    I already told to my GP that I need to urinate often and he asked me if it burns when I urinate and I told him no and he replied to me that as a consequence there is nothing to worry about but it seems to me that this symptom of burns urinating concerns problem with the bladder not with the prostate. Moreover when I ask him for a urine test he replied to me that this will not detect the cause of my weight loss

    I have also the following others symptoms:

    1. Sometime I have a big need to urinate quickly but when I urinate it is often only a little (but I do not need to urinate during the night)

    2. When I open my bowel the morning often I need to do this two times often the second time about 20 or 30 minutes after the first time

    3. It seem to me that I am very sensitive to pollution because when I go where there is a lot of traffic I have some problems breathing

    I do not know if it will be good I ask also to the consultant for a digital rectal examination (DRE) because I read that it can detect prostate cancer

     
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    Old 02-15-2016, 10:19 AM   #6
    window1
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    Re: Which tests to discover reasons for unexplained weight loss

    I have loss more weight now I am at 72kg.

    I have done a colonoscopy which has shown nothing. I have done also a CT scan of my chest on week ago. On Thursday I will have another appointment with the consultant and I will be given the result of this CT scan but if it shows something of serious I think that the hospital would have phoned me. I also had a urine test and I am waiting the result

    The Gastroscopy shows that I have oesophageal dysmotility with hiatus hernia and H pylori associated gastritis and I have been given a one-week treatment to eradicate the H pylori. However I have no pain or diarrhoea. And my appetite is good so I do not know if only advanced H pylori associated gastritis can cause loss weight

    In the report from the consultant it is stated that “his investigation to date have not yielded a clear reason for this loss weight” so I do not know if the H pylori is the cause of my weight loss

    I notice also that I have sharp bones in my legs.

    I have always looked like younger that I am really and when I was a boy people believed sometimes that I was a girl. Hence maybe I have hormones problems which can explain my weight loss

    I am worried because maybe the tests have shown nothing because I have a serious disease which is at an early stage or immediate stage

    I am worried also because I have heard that the liver which deals with fat can work even if part of it work property

     
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