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  • Statins do not Protect Against Alzheimer's

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    Old 08-10-2005, 11:10 AM   #1
    babydog
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    Statins do not Protect Against Alzheimer's

    I just read an article dated today that states that statins do not prevent Alzheimers's disease as was orginally thought. But they are still thinking that it might be preventive if it is taken early before symptoms begin.

    Bottom line, it was not the magic bullet for Alzheimer's they thought it was.

    Reminds me of when it was determined that HRT did not prevent heart disease but actually increased the risk!

     
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    Old 08-10-2005, 04:03 PM   #2
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    Re: Statins do not Protect Against Alzheimer's

    Quote:
    Originally Posted by babydog

    Bottom line, it was not the magic bullet for Alzheimer's they thought it was.
    I'll go even further than that. These drugs are no magic bullet for anything. In fact, with the way these drugs are being doled out like candy to millions of people, they're far more likely to cause harm to more people compared to the ones who are actually helped.
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    Old 08-12-2005, 10:09 AM   #3
    cathyinto
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    Re: Statins do not Protect Against Alzheimer's

    Quote:
    Originally Posted by ARIZONA73
    I'll go even further than that. These drugs are no magic bullet for anything. In fact, with the way these drugs are being doled out like candy to millions of people, they're far more likely to cause harm to more people compared to the ones who are actually helped.
    Oh, you mean like the increased risk of heart failure, or the increased risk of cancer?

     
    Old 08-12-2005, 04:12 PM   #4
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    Re: Statins do not Protect Against Alzheimer's

    Quote:
    Originally Posted by cathyinto
    Oh, you mean like the increased risk of heart failure, or the increased risk of cancer?
    Well, yes that and any other insidious maladies which may develop from long-term usage of these drugs, including neuropathies, cognitive impairment, muscle damage, etc. Don't forget, doctors aren't just prescribing these drugs to people who have existing heart problems. They are prescribing them to a much more broader segment of the population, including young healthy people who currently have no health problems. By doing this, I think we are opening a Pandora's box which will lead to nothing but trouble for a great many people.
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    Old 08-13-2005, 10:24 AM   #5
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    Re: Statins do not Protect Against Alzheimer's

    babydog,

    Statins were never touted as a "magic bullet" for Alzheimer's.

    And I doubt there were any people who were taking statins to ward off Alzheimer's or to cure it.

    Last edited by Lenin; 08-13-2005 at 10:26 AM.

     
    Old 08-14-2005, 11:12 AM   #6
    babydog
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    Re: Statins do not Protect Against Alzheimer's

    Quote:
    Originally Posted by Lenin
    babydog,

    Statins were never touted as a "magic bullet" for Alzheimer's.

    And I doubt there were any people who were taking statins to ward off Alzheimer's or to cure it.
    Hello Lenin,

    I recall several months hearing a report on the evening news that reported on research claiming statins cut the risk of colon cancer. Later on another news report came claiming statins cut the risk of Alzheimer's. The news reports will make you looney! What prevents something one day, either doesn't prevent or even causes it the next day!!

    I compare this to HRT or prempro for women because although hormone replacement therapy was originally supposed to be taken for the discomforts of menopause, eventually scores of women who didn't even have such discomforts wound up on HRT because research showed that it prevented certain cancers and heart disease. Now that that has been finally disproven, a news report came out a few weeks ago that basically said, "Leave menopause alone!!", meaning only those women who really need HRT should be placed on it and only for the shortest time period needed.

    The fact that a new research report shows that statins do not cut the risk of Alzheimer's would seem to indicate that statins may be on their way to going the way of HRT and no longer the "trendy" drug to be taken by all. This may be the beginning of a new trend which might show statins being offerred only to those patients who absolutely need the medication and not prophylactically to scores of Americans with mild to borderline numbers in an effort to prevent this or that. Call me untrusting, but I do feel that these research reports are often funded and released by the pharmaceutical companies to cajole viewers that may be sitting on the fence when it comes to such drug therapies.

    I could be wrong Lenin, but I can't help but think that eventually a report is going to come out that reads, "Leave cholesterol alone!!" and dispense only to those patients that really need it. I am currently on Niaspan and feel that I will probably end up going on statins at some point and have resolved myself to that eventuality.

    Mind you there are millions of Americans today who need to be on statins and are not on them either because they can't afford the drugs or don't even go to the doctor enough because of cost and don't even know they have high cholesterol. Such is the state of healthcare in this country.

    Just my opinion ofcourse.

     
    Old 08-15-2005, 09:34 AM   #7
    cathyinto
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    Re: Statins do not Protect Against Alzheimer's

    Quote:
    Originally Posted by Lenin
    babydog,

    Statins were never touted as a "magic bullet" for Alzheimer's.

    And I doubt there were any people who were taking statins to ward off Alzheimer's or to cure it.
    Actually they were. Small study with positive results, suggesting a larger study was needed. Didn't read that study, but know Dr. Golomb was finding exactly the opposite and she was dealing with a few more people .

    I get very concerned when anybody quotes studies with 20 or 30 people as the answer for anything.

     
    Old 08-16-2005, 11:10 PM   #8
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    Re: Statins do not Protect Against Alzheimer's

    My husband was mis-diagnosed with Alzheimer's "from" taking statins for 8 years.
    Neurologist wanted my husband to continue taking statins AND Alzheimer's drugs.
    We said "no Thank You". Fired the PCP and Neuro, and found a doctor that "understands" nutrition and nutritional supplements.

    Hubby is taking 200mg of CoQ10 (and other supplements) to help his recovery from memory loss and a host of other statin side effects.

    Frankie

     
    Old 08-17-2005, 09:55 PM   #9
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    Re: Statins do not Protect Against Alzheimer's

    I haven't been on for awhile. My Dad went back to the Neurologist for tests last week. He has remained stable. He has been off of Zocor since early June 2005 but the doctor doesn't think its the drugs that are effecting his memory. He feels its Alzheimers and prescribed Aricept on this last Monday, August 15. We don't know what to think. Very upsetting. He is 61 and is diabetic. No history of AD in our family. My grandfather, my Dad's Dad is almost 87 and his slowing down but no signs and my grandmother just turned 82, my Dad's Mom and both are doing well for their age. All of the problems began about 7months for my Dad after he started on the Zocor in Spring of 2003. I went with my parents to the appt. and this doctor at the University of Iowa Clinics does not believe me when I say that it could be statin drugs. What do I do? I want to get a second opinion and I feel Mom and Dad do too. We are looking at Mayo or U of Wisconsin Clinics in Madison. Any words of encouragement or advice would be appreciated. This is so stressful on my family.

    Thanks!!!

     
    Old 08-17-2005, 10:38 PM   #10
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    Re: Statins do not Protect Against Alzheimer's

    Quote:
    Originally Posted by dak2005
    All of the problems began about 7 months for my Dad after he started on the Zocor in Spring of 2003. I went with my parents to the appt. and this doctor at the University of Iowa Clinics does not believe me when I say that it could be statin drugs. What do I do? I want to get a second opinion and I feel Mom and Dad do too. We are looking at Mayo or U of Wisconsin Clinics in Madison. Any words of encouragement or advice would be appreciated. This is so stressful on my family. Thanks!!!
    Hi DAK,

    Most Doctors still will not admit that statins are causing cognitive disorders even though there is clear evidence that they do. We opted not to take Aricept. The Neuro was a bit perturbed with us. Said not to come back unless something changed.

    My husband had a CT scan (normal) and PET scan (normal). The PET scan shows brain activity VS mass. He also had Neuropsychological testing. This is where he scored low and they ASSUMED he had Alzheimer's. Basically the Neuropsychologist said, "If your husband gets better it's not Alzheimer's. People with Alzheimer's don't get better." My husband is getting better.

    Definitely get a second or third opinion if necessary.

    Search the internet, do your research and make copies of studies that support your suspicions.

    We need to be just as smart and sometimes smarter than our doctors. They are humans and make mistakes too.

    And most of all, go with your gut feeling.

    Hope this info helps. I know how difficult it is to make decisions without guidance.

    Frankie

     
    Old 08-18-2005, 09:21 AM   #11
    dak2005
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    Re: Statins do not Protect Against Alzheimer's

    Frankie~

    Thanks so much for your reply. I just called my Mom and told her what you said. She wants me to ask you a few more questions. At what point did you and your husband notice the memory problems, after a few years, few months etc? How old is your husband? What dosage of the statin drug was he on and which one? Lipitor, Zocor etc? Any other side effects? Fatigue, sleep problems? How long has he officically been off of the statin? I think I have asked the main questions. Thank you again so much. How is he doing today, is he working?

    DAK

     
    Old 08-18-2005, 12:22 PM   #12
    heart44
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    Re: Statins do not Protect Against Alzheimer's

    Quote:
    Originally Posted by dak2005
    Frankie~ Thanks so much for your reply. I just called my Mom and told her what you said. She wants me to ask you a few more questions. At what point did you and your husband notice the memory problems, after a few years, few months etc? How old is your husband? What dosage of the statin drug was he on and which one? Lipitor, Zocor etc? Any other side effects? Fatigue, sleep problems? How long has he officically been off of the statin? I think I have asked the main questions. Thank you again so much. How is he doing today, is he working? DAK
    Hi Dak,

    Hubby's stats:
    Quad bypass at age 52; he is 61 now.
    Took Lopid first, but it did not agree with him (stomach/intestinal trouble).
    Then Zocor for 1 years - side effects, muscles, but memory not affected. He was switched to Lipitor because Zocor did not lower his triglyceridces.

    Then Lipitor for 5 years - after about 3 years is when I started to notice memory problems and this was around the same time dose was increased from 10mg to 20mg. Memory loss started very slowly, was very easy to attribute it to "inattention", etc. He loves to play golf, but would come home very upset saying the guys said he was "fudging" his score. The reality was he could not remember how many strokes he'd taken. He became very irritated (would snap at me for stupid things), anti-social, took several naps a day (yes, very fatigued). He had trouble with "instructions". This one is hard to expalin. He has always had an excellent understanding of how electronic equipment works. He would draw diagrams for me so I would know how everything works. Now I draw diagrams for him.

    It was at this point I realized there was a serious problem:
    He asked me the same question 6 times, just minutes apart and I answered him each time..... the last time very snappish.... we had an argument, but once we settled down, realized something was seriously wrong. After reading Dr Graveline's description of TGA (transient global amnesia) it all started to make sense.

    One thing that definitely has not been affected..... he is an excellent driver and that has not changed one bit. His trouble with "problem solving?" does not affect decision making.

    He did try red yeast rice for 6 months after stopping Lipitor, thinking that because it was "natural", it would not have side effects. It produced all the same side effects as Zocor and Lipitor.

    He has not taken any type of statin for one year. His memory is recovering slowly and he's feeling much better everyday. I can't stress enough that statin side effects do not always occur soon after starting the drug. After years of depriving our bodies of essential cholesterol, things start to fail very slowly.

    Some say that it can take as long as 2 years to rid our bodies of statins. Unfortunately, some people do not recover completely.

    Any time you have any questions, just let me know,
    Frankie

     
    Old 08-18-2005, 08:00 PM   #13
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    Re: Statins do not Protect Against Alzheimer's

    Frankie~

    Thank you so much!! Everything you stated sounds so familiar. Fatigue is one that has been a problem too. My Dad is a former dairy farmer so afternoon naps were not always unusual but he is so tired and the energy is not there. The naps are quite frequent. After quitting farming in 1996 he went into road construction which is a very stressful job with all of the traveling. Dad changed part of the barn where we had cows and made it into a woodshop soon after he quit farming. It is his get away. Just loves working with wood. He has made so many things for me and Mom and friends and family. I sure hope he can make some things very soon. He is so good at working with machines and he hasn't made anything.... just can't focus and part of it is the self-confidence as well. Mom tries so hard to think back when she noticed things and she can honestly say it was about 7 to 8 months after he started the Zocor. My Dad's sister remembers telling them that she really didn't want him to go on the drug even back in 2003. At the time a friend of the family was put on Lipitor, not sure of the dosage but he was also farming and milking cows at the time and at one point he forgot what cows he had milked and could not focus, concentrate, it was a mess. He even got to an intersection that he knows very well and couldn't figure out which way to go. So scary!! My Dad hasn't been driving, my Mom has but she did let him drive uptown this last Tuesdayaand I think he did okay. I could go on forever. I appreciate your information so much and pray that is the same thing as your husband. Take Care!!!

    DAK

     
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