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  • Elevated hs-CRP- How Bad Is It?

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    Old 10-17-2007, 05:16 PM   #16
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    Re: Elevated hs-CRP- How Bad Is It?

    Very provoking, Mark.
    And I appreciate many of your viewpoints on the uneasy relationship between much of today's 'science' and its funding sources. I'm no fan of statins and I'll admit I am decidedly disenchanted with many aspects of my medical care. I will certainly be looking at work of the people you referenced.
    Like you, I have had a very positive experience on a low-carb (Atkins-like) diet. In fact, 4 years ago and before I started to have back trouble, my cholesterol numbers were the best they'd ever been and that was 3 years into Atkins. Foolishly, I let my GP talk me into Zocor because she thought I could do better. I became very ill but we didn't catch it because of my back problem. We atttributed all of the symptoms to my back! It wasn't until after 2 major surgeries and some scary neurological symptoms that a specialist questioned the Zocor and we figured it out. What a nightmare!
    Anyway, I wouldn't be questioning the diet if it weren't for the hs-CRP. I really need to find some primary research that explains to me the link between inflammation and saturated fats. So far, I don't find it.
    Mark, do Type I diabetics typically have elevated CRP? Thanks for taking the time to reply so thoroughly. Much appreciated. Suzy-Q

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    Old 10-17-2007, 06:33 PM   #17
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    Re: Elevated hs-CRP- How Bad Is It?

    Originally Posted by Suzy-Q View Post
    ... Mark, do Type I diabetics typically have elevated CRP? ...

    Research suggests that elevated CRP is associated with type 1 diabetes, but it is not convincing. According to one study, a significant correlation was found among older women who are also insulin resistant. But there was no evidence of this among men. It kind of begs the question whether type 1 diabetes has anything to do with it. Maybe insulin resistance is the real culprit.

    Research shows that CRP levels rise as the HBA1c (level of blood glucose) rises. What is not clear is whether this inflammation is caused by high glucose levels or by something else that happens to diabetics. Unfortunately, type 1 and type 2 diabetics are lumped together for most research purposes. Type 2 diabetics typically have high insulin levels, and the poorer glycemic control is, the higher those insulin levels are likely to be. High insulin levels are known to be inflammatory, so this could have a bearing on CRP results.

    A study found that elevated CRP predicts the onset of type one diabetes. Here is an exccerpt from the conclusion :

    The finding of elevated CRP levels in infants and young children before the onset of type 1 diabetes adds to the evidence that the disease is an immunoinflammatory disorder. The elevated CRP levels may provide an additional marker for risk of progression to type 1 diabetes.
    I have had my CRP tested and, after 30 years of being a type 1 diabetic, it is very low. Maybe the CRP level drops off again after the damage has been done and there are no more insulin producing beta cells to be destroyed. Who knows ...

    Type 1 since 1977. On Lantus, Novorapid and Actrapid.

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