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    Old 01-01-2008, 05:23 AM   #1
    zombie dude
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    Unhappy hypertension controlled by nitric oxide?

    Hi: new to this group. Has any one have any information on the use of
    nitric oxide as a vasodilator ?. I looking for a way to cut down on over
    medication. Having to meany bad reactions. Iam on clonidine x3 per day,
    norvasc 10mg x1,hydrochlorot 25mg x1,atenolol 50mg x1, lisinopril 10mg x1,
    mirtazapine x1 at bed time. This is a sleep aid for my sleep Apena.
    It seems every year and new doctors want to perscripe more drugs.
    These make me vary crogy and find it hard to pay attention behind the wheel
    and imposible to make a good inpression for a job interveiw.
    slowly losing wife and home and little of my life savings to my BPH.
    zombie dude.

     
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    Old 01-01-2008, 06:05 AM   #2
    cartner
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    Re: hypertension controlled by nitric oxide?

    Hi,

    Welcome to this great board, actually I can't help you with your nitric oxide question. But I will try to tell you my experience, first of all I think that you are over-medicated. Could you tell us what is your average BP before taking all these meds and with it?

    I have tried ACEs, like lisinopril, and ARBs, like Cozaar and Atacand. I have had many bad side effects, I can say that life is impossible while being on any ONE drug of those classes. Although that both my parents used those drug classes for many years without any side effects. Also, I think that maybe 1 or 2 drug is enough to control your BP if you are healthy and exercise regulary.
    After some research and great help from people here, I have came to my best drug class and my best drug combination . Now I take 5 mg of Norvasc plus 2.5 of Zebeta, a beta-blocker. My blood pressure is great and I'm fine, when Zebeta lowers my heart rate very much I would replace it with another 5mg of Norvasc. But so far so good.
    My advice is to find a good new doctor that will listen to your side effects and start with you maybe with only Norvasc, as a beginning and see what would happen and what would you feel.
    Good luck and please let us know what is going on with you.
    Michael

     
    Old 01-01-2008, 06:53 AM   #3
    zombie dude
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    Re: hypertension controlled by nitric oxide?

    I'm 49 male . have been on and off lots of diferent meds since I was 18. My bp realy went up when I broken my left leg in 7 placees all below the knee. Had surgery. all most
    up to speed. can only walk 1 - 2miles per day. before accident I was doing fair 200LB.s
    walking and biking about 5 miles per day, my BP was 140/90. Now its was 239/150
    with out meds. Now its 138/77 average. my weight is 240lbs. 5'9''. Doc said not to
    exercise. The pain in all my joints and legs is a 7 on a scale 0-10.

     
    Old 01-01-2008, 07:23 AM   #4
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    Re: hypertension controlled by nitric oxide?

    Yes that is very high but I still think that you need to see another doctor. We really need doctors who admit that those drugs can cause serious side effects for AT LEAST some of us. My doctor seems to be very understanding, when I tell him that Beta-Blockers lowers my heart rate too much he believes me.
    Good luck and I hope that other members will give you useful information.
    Michael

     
    Old 01-02-2008, 08:35 AM   #5
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    Re: hypertension controlled by nitric oxide?

    Zombie Dude, I'm glad someone has mentioned nitric oxide. Yes, it is supposed to act as a vasodilator. Supposedly you can increase your levels of nitric oxide by taking various supplements (not nitric oxide itself). The main one I hear about is l-arginine. It's supposed to work pretty well. The bad thing about it is that you have to take a ton of it (pills) to make a difference. Like a minimum of 3 grams a day. Supposedly you can take about 20 grams safely, but for me that's way too much experimenting. I bought some, but I was afraid to take even the 3 grams because I am the 'side effect queen'. I took 1.5 grams for a few days and it did seem to help a little bit, but not near as much as I needed. Then later on I found out that they have a liquid form of l-arginine that will give you about 5 grams in one dose. I haven't tried it yet. I got really nervous about my bp readings and decided to get on a baby dose of Norvasc. Which isn't doing much either, but I think I may have some stomach issue that is keeping my BP up and refuse to take a higher dose until I can get my gastrointestinal system checked out. Research l-arginine, it may be your answer. Good luck.

     
    Old 01-02-2008, 08:18 PM   #6
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    Re: hypertension controlled by nitric oxide?

    [Hello Zombi dude,

    Welcome to the boards!

    First off, I have mentioned the importance of nitric oxide off and on in past posts when I became aware of the importance of this gas in the regulation of high blood pressure. It is theorized that sleep apnea reduces the production of this gas and by treating sleep apnea, you can elevate nitric oxide and lower your blood pressure. I suspect a similar thing happens when one does the breathing exercises but haven't researched this enough to support my suspicions. However, I have NEVER come across info suggesting that supplements will increase nitric oxide output so beware of any supplement which claims to do this.

    Why are you taking a med for sleep apnea? I ask, because I am not at all familiar with this method of treatment....I have a cpap and others I know have had surgery or use dental devices but I have never heard of someone taking medication for apnea...is yours obstructive? central? mixed?

    FYI, I, too, have apnea but found that some of the meds made my sleep problems worse, for whatever the reason. My sleep disturbances on meds were worse than with untreated apnea----I blamed the apnea for 3 years before realizing that I didn't have sleep problems as severe as those as I was experiencing before going on bp meds. When you get restorative sleep, the pressures drop.

    I agree with the poster that suggests you see another doctor!!! Joint pain of 7 on a scale of 10 is SERIOUS, especially, since at least one of the meds (clonodine) you are taking can cause permenant problems!!! And IF your pressures are as high as you say they are (and not artificially elevated due to over the counter pain meds, vitamin/herbal supplements, improper readings, etc), it is very likely that given your high readings, you are experencing high blood pressure that is caused by another condition, that if treated, could reduce your pressures and reduce your need for medication.

    For the sake of your health, your relationships, and your financial well being I do hope you seek out a specialist in blood pressure management. I say this because in three years I lost my job, my life savings, and my relationships suffered and this could have been avoided had I seen a physician who was versed in the prevention, detection, and treatment of hypertension.

    Bethsheba

     
    Old 01-03-2008, 01:22 AM   #7
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    Re: hypertension controlled by nitric oxide?

    I completely agree with Bethsheba, I was one of those people that think that all doctors are the same (because they are all graduated from medicine schools). I was very wrong , you need to find a doctor who can listen to you. For example, when I tell my doctor that Cozaar caused a lot of side effects he believed me. Others didn't and said to me that I have to be STRONG and I have to wait more time.
    Good luck and I hope you will be fine soon
    Michael

     
    Old 01-11-2008, 12:10 PM   #8
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    Re: hypertension controlled by nitric oxide?

    To use supplements to lower Blood Pressure with Nitric Oxide, I will recommend to you, to read these two books, the most important is the first one, as it was writhed by Dr Ignarro who won the novel award with his investigations about it:

    NO More Heart Disease
    by Dr Louis Ignarro who shared the Nobel Prize

    The Arginine Solution
    by Robert Fried

    ralaco01

     
    Old 01-12-2008, 04:17 AM   #9
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    Re: hypertension controlled by nitric oxide?

    Quote:
    Originally Posted by ralaco01 View Post
    To use supplements to lower Blood Pressure with Nitric Oxide, I will recommend to you, to read these two books, the most important is the first one, as it was writhed by Dr Ignarro who won the novel award with his investigations about it: ...

    ralaco01
    Hello rlaco,

    I have done some research on the info you have provided....

    1. Although the supplements (Niteworks) are being promoted as a preventive against cardiovascular disease , the product hasn't been studied in humans.

    2. Some sources think that Nobel Prize winner Louis Ignarro, Ph.D, who has a substantial financial interest in the promotion of supplements, is using his recognition/accomplishments to increase sales and thus his financial position.

    Even though products are endorsed by prominent people, or doctors, or scientists, or whatever does not guarantee that the products do what the promotors say they will do. We need to question more, read more, compare more before we pop something into our mouths...and that includes prescripton and over the counter meds and supplements!

    Bethsheba

     
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