It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....

High & Low Blood Pressure Message Board

Side effects of Zestril

Post New Thread   Closed Thread
LinkBack Thread Tools Search this Thread
Old 09-04-2003, 05:53 AM   #1
Join Date: Sep 2003
Location: Yorktown Heights, NY, USA
Posts: 2
Post Side effects of Zestril

Recently I was diagnosed with high blood pressure, which we are trying to get under control using various medications/doses as trials. I have been on Lisinopril-HCTZ 20/12.5 (also called Zestril, I believe) for about a month. During the first week I developed strong aches in the bones/joints of my thumbs. This happened rapidly. The aches are constant all day, but more severe in the morning. The doctor thinks it's arthritis. Has anyone had the experience of a medication unleashing an arthritic condition that had never occurred before? I would appreciate any thoughts that anyone out there may have about this. Thanks.

Sponsors Lightbulb
Old 09-04-2003, 10:49 AM   #2
Senior Veteran
Join Date: Jan 2003
Location: California, U.S.A.
Posts: 3,088
zuzu8 HB Userzuzu8 HB Userzuzu8 HB Userzuzu8 HB Userzuzu8 HB Userzuzu8 HB User

Hi Keliza- The fact that your pain came on so suddenly and coincided with starting Zestril, sure makes Zestril look guilty.

In controlled studies, arthritis is not listed as a problem with this drug....However the following adverse reactions, although rare have been reported in uncontrolled studies and during marketing..
Arthritis, arthralgia, neck pain, hip pain, low back pain, joint pain, legpain, knee pain, shoulder pain, arm pain, lumbago.

Seems to me that arthritis creeps up on you and at the beginning would be transient in nature and not bilateral (both thumbs) so suddenly...

But I'm not a doctor, so can't advise you more than to talk again with yours, who of course will be MAD at you for getting info "from the Internet"! (Just tell him that you read the pharmaceutical company's monograph which you obtained from your pharmacy on request..That'll shut him up!)

zuzu xxx

[This message has been edited by zuzu8 (edited 09-04-2003).]

Old 09-06-2003, 12:00 PM   #3
Join Date: Sep 2003
Location: Yorktown Heights, NY, USA
Posts: 2

zuzu8 -
Thanks so much for taking the time to give some thought to my problem. It is just puzzling to me (as I am sure is the case with anyone who develops unsual symptoms rapidly). My doctor is very nice, but busy, so I basically try to take responsibility for my own medical care as much as I can. The swelling and soreness has continued, although it is limited to my thumbs and has not affected any other joints (strange, I know!). I have applied both heat and ice packs with no noticeable improvement. I will finish out this month's Zestril prescription (which has been the first medication I've been on that has finally lowered my blood pressure somewhat) and if the condition persists, I guess I will have to try something else. Any suggestions?

[This message has been edited by KELIZA (edited 09-06-2003).]

Old 09-07-2003, 10:26 AM   #4
Senior Veteran
Join Date: Jan 2003
Location: California, U.S.A.
Posts: 3,088
zuzu8 HB Userzuzu8 HB Userzuzu8 HB Userzuzu8 HB Userzuzu8 HB Userzuzu8 HB User

KELIZA- Not knowing your medical history, age, gender, weight, whether you exercise, smoke, drink etc... or which drugs you've tried already, I wouldn't attempt to advise you on a particular drug, especially since there are so many.
Perhaps if you give us some info about youself and what you've tried already and any other health issues you may have, (if any) I could suggest a "route" to try....

zuzu xx

Old 01-02-2004, 07:52 AM   #5
Junior Member
Join Date: Dec 2003
Location: wales
Posts: 31
en08 HB User
Re: Side effects of Zestril

I developed a terrible neck ache after taking lisinopril. My doctor said it was my age! After 6 weeks and taking the codliver oil that I had for the dog it got better although I had numerous other side effects. My thumbs hurt as well but the pain as not so bad. Ive just given up the drug.

Old 01-02-2004, 12:27 PM   #6
Join Date: Apr 2002
Location: Jersey City, NJ
Posts: 2,896
zip2play HB User
Re: Side effects of Zestril


One thought....have your uric acid checked (or just pull out some blood tests if you have them).

Thiazides are notorious for CAUSING gout in people who are close to urate saturation.
HCTZ did this to me.
Until I got a classic case of podagra (gouty bunion joint attack) it was one awful joint after another seemingly out of the blue. For me mostly in the instep but occasionally in the hand, elbow and wrist....and a chronic thumb pain.....
Took a while to get a good diagnosis (and my doctor was ZERO help).

Believe it or not, the bolt of eureka hit when I read a quote from the humorist Lionel Trilling: He was asked what he learned in life that was the most valuable he said:
"Really, only one thing. When you have a lump on your thumb, it's gout!"
I couldn't believe my eyes!

If you see a blood uric acid over 6.0, it's a good bet that gout caused by the thiazide is doing it.

(In order to keep electrical balance in the body when sodium is excreted, urates are retained....there's the rub)

Last edited by zip2play; 01-02-2004 at 12:32 PM.

Old 01-07-2004, 02:25 PM   #7
Join Date: Aug 2002
Posts: 316
Re: Side effects of Zestril

Hi All~
I am on this medication and I haven't suffered any side effects from it. I've been on it for about 5 years or so. Just thought I'd add my two cents.

Old 11-02-2004, 06:51 AM   #8
Join Date: Nov 2004
Posts: 1
yak54 HB User
Re: Side effects of Zestril


Last edited by yak54; 11-02-2004 at 06:52 AM.

Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
lisinopril Side Effects Ronnie99 High & Low Blood Pressure 12 08-07-2006 02:38 PM
Are There any BP meds w/o side effects? octoberbride High & Low Blood Pressure 12 02-17-2006 11:02 PM
? about lisinopril side effect patti23 Drug Interactions / Side Effects 0 01-20-2005 06:29 PM
side effects of lisinipril bharkins High & Low Blood Pressure 1 06-20-2004 03:26 PM
my blood pressure medicine...can this be a side effect? frisfluf High & Low Blood Pressure 2 04-16-2004 07:08 AM
B/P Side-Effects BlueIsland High & Low Blood Pressure 3 12-01-2003 08:58 AM
BPmeds and side effects Fay123 High & Low Blood Pressure 5 10-20-2003 01:36 PM
Side effects of teveten/norvasc/hydrochlorothiazide Finn High & Low Blood Pressure 17 06-26-2003 11:36 AM
Zestril and Parkinson's RexWig Parkinson's Disease 1 04-28-2003 07:06 PM

Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off

Sign Up Today!

Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

I want my free account

All times are GMT -7. The time now is 07:44 PM.

Site owned and operated by HealthBoards.comô
© 1998-2018 HealthBoards.comô All rights reserved.
Do not copy or redistribute in any form!