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Diuretics and Weight Gain!

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Old 03-03-2009, 10:07 PM   #1
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Diuretics and Weight Gain!

Why would High Blood Pressure meds with a diuretic in it, cause you to gain weight?
I can't seem to find a BP med that doesn't just about kill me. I was on Toprol XL and had no side effects at all, but my BP kept going up. Dr. put me on Diovan and the side effects were horrible, couldn't even function.
Took Benicar HCT and same thing, could barely walk from one room to another, even though it lowered my BP, but my Pulse was super high.
Now he wants me to try Bisoprolol/HCTZ (Ziac), but everywhere I've checked everyone says it caused them to gain lots of weight. I have such a low tolerance to meds, so he's starting me at 5mg. I'm 5'1", 111 lbs., am very comfortable with my weight and don't want to gain, cause that's not good for you either.
I really don't understand how anything with a Diuretic makes you gain, hopefully someone knows

Last edited by busy223; 03-03-2009 at 10:08 PM.

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Old 03-04-2009, 05:30 AM   #2
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Re: Diuretics and Weight Gain!

I dont know what in BP meds cause weight gain, some do though. I am not sure about yours but on mine which sounds like yours I gained 20-30 pounds within a year. I have since got it off with diet and exercise.

Just watch what you eat.

Old 03-04-2009, 12:02 PM   #3
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Re: Diuretics and Weight Gain!

What happens is that diuretics alter the way the body metabolizes lipids (fats) and glucose. This is what ultimately results in weight gain.
In addition to the above metabolic effects, diuretics (hctz in particular) also alter some electrolyte levels, such as potassium and magnesium. Blood levels of several other substances can also be affected. These adverse effects can be limited by keeping the drug doses low. Many drugs-including some blood pressure medications-affect metabolism and can cause weight gain. Weight gain is not as big a deal as the potential consequence of going without the medication.


Old 03-04-2009, 04:40 PM   #4
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Re: Diuretics and Weight Gain!

I've gained 20 lbs in the last 6 yrs since being on Labetalol & HCTZ. I hate it. I was able to keep my weight in the 140's before that. The beta blockers slow everything down.

But there is hope. We have to be very selective in our eating. Counting calories for me is the only way so that I don't go over my very rigid bottom line. Actually, I find that I eat better when I am watching my calories because I make food that I really enjoy & don't waste calories on stuff I don't really like. For example, for my birthday, I just ate the icing. I don't really like the cake part anyhow. It's worth the effort. I just started seeing a loss so I think I'm on the right track. FAm

Old 03-04-2009, 04:45 PM   #5
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Re: Diuretics and Weight Gain!

HCTZ works for some people in doses as low as 6.25mg/day according to some experts. So it pays to tritrate that is start with a very low dose & work up until your b/p stabilizes. It may take up to a month for HCTZ to work. I wouldn't take a combo pill until I established the correct dose of both drugs. Remember the higher the dose the more possibilities of side effects.

I've been thorough many drugs & some horrendous side effects so I know where you are coming from. Fam

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