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Persistent dysplasia - no HPV

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Old 04-13-2005, 10:18 AM   #1
Join Date: Apr 2005
Posts: 2
bostonbeth HB User
Persistent dysplasia - no HPV

Hello -

I'm 25 and began having abnormal paps 1.5 years ago. Since my first abnormal pap, my doctor has done 6 paps, all which came back with very low dysplasia.

After the results of my first abnormal pap, my doctor tested me for HPV, since HPV is a major cause of dysplasia. It came back negative. She took a biopsy of cervical tissue which also came back negative. Two months later I was seen again. Again, dysplasia was present, she ran a HPV test and biopsied and both returned negative. Two months afterwards she tested and biopsied a third time, with the same results. A full STD check was also done, with all negative results. Since all 3 HPV tests were negative, she ruled out HPV, which is said to cause dysplasia in 95% of cases.

This morning I went back in for a checkup, had a pap and a colpo. The dysplasia region was still present, although low grade again. She took a fourth biopsy just to be safe. So, in 1.5 years I have had 6 paps, 4 biopsies and 3 HPV tests - and everything has been negative, though the mild dysplasia is still present. I asked her what could be causing the dysplasia and she said she didn't know - it could be a genetic thing or something else. She said that I could have the legion removed but it was up to me to decide. Since I don't have a disease and nothing is spreading or complicating, or causing problems, why have a surgical procedure that could potentatially cause fertility issues? My doctor said we could discuss it further once my lab results come back.

So my question is - has anyone else experienced this? It's persistent but a cause cannot be found. I trust my doctor and know if I were at risk she'd advise me correctly - but should I be concerned? Or seek a second opinion?

Thanks for any input.

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Old 04-13-2005, 02:07 PM   #2
Join Date: Nov 2004
Posts: 452
gingertea HB Usergingertea HB Usergingertea HB Usergingertea HB Usergingertea HB Usergingertea HB Usergingertea HB User
Re: Persistent dysplasia - no HPV

I also have mild HPV. My doctor told me we would just do colposcopies and biopsies every six months until two in a row come out clear. I'm past child bearing years, so that is not an issue, but I see no reason to have the lesion removed unless it worsens. I am more afraid of the cure, than the cause! I should add that my pap smear came back normal.....the only reason I had the colposcopy and biopsies in the first place was because my cervix is misshapen.
Ginger Tea

Old 04-13-2005, 02:42 PM   #3
Join Date: Apr 2005
Location: America the beautiful
Posts: 201
ladivapr02 HB User
Re: Persistent dysplasia - no HPV

boston and why the doctor hasnt freezed yet?

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